具有非特异性抗病毒活性的免疫刺激剂在儿童慢性腺样体炎复杂治疗中的应用前景

E. Pokrovskaya, S. V. Khaliullina, V. Krasnozhen, E. Mannanova
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引用次数: 0

摘要

本文介绍了肌苷pranobex在手术干预后3度咽扁桃体肥大患儿中预防咽扁桃体炎复发和术后期腭扁桃体代偿性肥大的研究结果。对355名3 ~ 7岁诊断为咽部扁桃体三度肥大的儿童进行了检查。实验室检测方法包括定性检测鼻咽粘膜潮红中嗜淋巴疱疹病毒(EBV、CMV、HHV-6)的DNA。本研究结果表明,肌苷pranobex纳入慢性腺样体炎合并疱疹病毒感染患儿的综合治疗在临床上是有效的,并有助于降低咽扁桃体肥大和代偿性腭扁桃体肥大的复发风险。
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Prospects for using immunostimulating agents with nonspecific antiviral activity in the complex treatment of children with chronic adenoiditis
The article presents the results of studies on using inosine pranobex in children with pharyngeal tonsils hypertrophy of the 3rd degree after surgical intervention to prevent the development of pharyngeal tonsillitis relapses and compensatory hypertrophy of palatine tonsils in the postoperative period. 355 children aged 3 to 7 years old with a diagnosis of pharyngeal tonsil hypertrophy of the 3rd degree were examined. Laboratory methods of examination included qualitative studies to detect DNA of lymphotropic herpesviruses (EBV, CMV, HHV-6) in flushes from the nasopharyngeal mucosa. As a result of the conducted research, it was revealed that the inclusion of inosine pranobex in the complex treatment of children with chronic adenoiditis with verified herpesvirus infection is clinically effective and helps to reduce the risk of recurrence of pharyngeal tonsil hypertrophy and compensatory palatine tonsil hypertrophy.
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