冠状病毒会导致在感染COVID-19之前没有糖尿病的人患糖尿病

Ziena Y.Jameel, Bassam B.Hasan
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摘要

冠状病毒病通过与血管紧张素转换酶2(ACE2)受体结合感染呼吸系统,在感染后5-6天内出现症状,发病初期伴有轻至中度症状,持续10-15天。但它有可能发展成严重的急性呼吸窘迫综合征(ARDS),导致身体多个器官的破坏,包括胰腺朗格汉斯岛的β细胞,导致1型或2型糖尿病和高血糖。该研究的目的是检测COVID-19患者的糖尿病,这些患者在接触病毒之前没有糖尿病,也没有糖尿病家族史。采用实时荧光定量PCR法鼻拭子诊断新冠肺炎。通过血糖、糖化血红蛋白(HbA1C)等血液检查检测糖尿病,通过二聚体(Dimer)、乳酸脱氢酶(LDH)、铁蛋白(Ferritin)、C反应蛋白(CRP)检测感染的急性期。从研究中获得的结果来看,该病毒导致的糖尿病患者比例为20%的I型,而80%的II型糖尿病患者。
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Coronavirus Causes Diabetes in People who Did Not Have Diabetes Before They Contracted COVID-19
Coronavirus disease infects the respiratory system through binding to the receptor of angiotensin-converting enzyme2(ACE2), Symptoms of the disease develop within 5-6 days after infection, accompanied by mild to moderate symptoms in the initial stage of the disease, and continue for 10-15 days. But it has the potential to develop into severe acute respiratory distress syndrome (ARDS), which leads to the destruction of multiple organs in the body, including the beta cells in the islets of Langerhans in the pancreas, causing type 1 or type 2 diabetes and high blood sugar. The aim of the study is to detect diabetes mellitus in people with COVID-19 who did not have diabetes and did not have a family history of the disease before they were exposed to the virus. COVID-19 was diagnosed by nasal swab through PCR Real-time. The detection of diabetes was through blood tests such as blood sugar, and glycated hemoglobin (HbA1C), and the acute stage of the infection was detected through Dimer, LDH, Ferritin, and C -reactive protein (CRP) tests. From the results that obtained during the research, it was found that the patient percentage with diabetes due to the virus is 20% of type I, while 80% diabetes of type II.
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