两例突发性注射器瘤的皮肤镜表现

Ryo Ogawa, N. Umegaki, Masayuki Urabe, S. Ishizaki, Masaru Tanaka
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摘要

爆发性水疱瘤是一种罕见的类型的水疱瘤,良性肿瘤的内分泌管,其特点是存在广泛的高色素丘疹的躯干,发生在青春期左右。在此,我们报告两例发疹性水疱瘤,表现出特征性的皮肤镜检查结果。病例1涉及一名21岁男子,他在19岁左右躯干出现大面积皮疹。临床检查显示小的棕色丘疹分布在躯干和两侧腋窝。鉴别诊断包括扁平疣和Darier病。病例2涉及一名67岁男子,他从20多岁起就意识到躯干上有发痒的棕色丘疹。病例1和2的皮肤镜检查显示均匀的浅棕色色素沉着,多灶性白色区域,周围有精致的色素网络,这是典型的突发性注射器瘤的特征。组织病理学检查显示真皮上部纤维间质内嵌有大量小导管和上皮岛状细胞。这些结果与病例1和病例2的诊断一致。对比皮肤镜和组织病理学检查,边界不清的白色区域对应真皮上部纤维间质,边界不清的区域对应真皮病变。因此,皮肤镜鉴别皮肤疣
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Two cases of eruptive syringoma presenting with characteristic dermoscopic findings
Eruptive syringoma is a rare type of syringoma, a benign tumor of the eccrine ducts, and is characterized by the presence of widespread hyperpigmented papules on the trunk with onset around puberty. Here, we report two cases of eruptive syringoma presenting with characteristic dermoscopic findings. Case 1 involved a 21-year-old man who had developed a widespread skin rash on his trunk around the age of 19 years. Clinical examination showed small brown papules spreading on the trunk and both axillae. The differential diagnoses included verruca plana and Darier's disease. Case 2 involved a 67-year-old man who had been aware of itchy brown papules on the trunk since he was in his twenties. Dermoscopy in cases 1 and 2 showed homogeneous light brown pigmentation with multifocal whitish areas and a delicate pigment network at the periphery, which are typical characteristics of eruptive syringoma. Histopathological examination showed numerous small ducts and islands of epithelium embedded in a fibrous stroma in the upper dermis. These findings were compatible with the diagnosis of eruptive syringoma in cases 1 and 2. On comparing the dermoscopic and histopathological findings of syringoma, the whitish area with unclear borders corresponded to the fibrous stroma in the upper dermis, and the unclear borders corresponded to the dermal lesion. Therefore, dermoscopy differentiate skin verruca
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