甲醛暴露对尼日利亚贝宁市殡葬业人员心血管指标的影响

Frederick Ebojele, V. Iyawe
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摘要

简介:研究了甲醛暴露对贝宁市殡仪人员心血管功能指标的影响。材料与方法:本研究共招募50名受试者,其中非殡葬业者10名,殡葬业者40名。按甲醛暴露时间(年)分为A、B、C、D、E五组,每组10人。A组为对照(非丧葬者),B、C、D、E组分别为0 ~ 5年、6 ~ 10年、11 ~ 20年、>20年的试验组。测量了人体测量参数以及一些心血管指标,包括脉搏率、收缩压(SBP)、舒张压(DBP)、脉压和平均动脉压(MAP)。使用GraphPad Prism 5.0版本进行统计分析。结果以均数±标准误差表示,方差分析比较检验值和对照值的均数,事后检验采用Student-Newman-Keuls检验,P < 0.05为差异有统计学意义。结果:结果显示,E组殡仪人员收缩压、舒张压和MAP明显升高。结论:长期接触甲醛会影响殡葬业者的心血管健康。
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Effect of formaldehyde exposure on some cardiovascular indices among morticians in Benin City Nigeria
Introduction: The effect of formaldehyde exposure on some indices of cardiovascular function among morticians in Benin City was studied. Materials and Methods: Fifty subjects were recruited for the study which included 10 nonmorticians and 40 morticians. Subjects were divided into five groups A, B, C, D, and E according to their duration (in years) of exposure to formaldehyde with ten subjects in each group. Group A served as the control (nonmorticians), whereas Groups B, C, D, and E served as the test groups with 0–5 years, 6–10 years, 11–20 years, and >20 years exposures, respectively. Anthropometric parameters were measured as well as some cardiovascular indices which include pulse rate, systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure, and mean arterial pressure (MAP). Statistical analysis was done using GraphPad Prism version 5.0. Results were presented as mean ± standard error of the mean analysis of variance was used to compare the means of test and control values, whereas post hoc test was done using Student‒Newman‒Keuls test and a P < 0.05 was considered as statistically significant. Results: Results showed significant increases in SBP, DBP, and MAP among Group E morticians. Conclusion: It was therefore concluded that prolonged exposure to formaldehyde could affect the cardiovascular health of morticians.
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