Pharmacodynamics of PanchatiktaGugguluGhritain AsthimajjagataVatawith special reference to avascular necrosis of femoral head

Avascular necrosis (AVN), is a condition that occurs when there is loss of blood supply to the bone, also known as osteonecrosis, bone infarction, aseptic necrosis, or ischemic bone necrosis. Based on pathogenesis and clinical sign and symptoms, it can be compared with AsthimajjagataVata. One of the popular and frequently used medications in the Ayurvedic medical systemis PanchatiktaGugguluGhrita. Panchatikta Guggulu Ghritahas been described in AstangahrudyamVatavyadiChikitsaAdhayayamwhich is indicated in Asthimajjagata Vata. Here is an attempt made on pharmacodynamics of Panchatikta Guggulu Ghrita in respect ofAsthimajjagataVata.