作为一种很有前途的人类和动物保护剂

A. Bownik, Z. Stępniewska
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引用次数: 63

摘要

摘要:异托碱是一种相容性的水分子结合溶质(渗透保护剂),由几种细菌在渗透胁迫和不利环境条件下产生。这种氨基酸衍生物可以在细胞内高浓度积累而不干扰自然过程,并可以保护细胞免受辐射或渗透胁迫。这篇简短的综述介绍了目前关于异托因对动物的作用的知识现状,并重点介绍了它在酶稳定、人体皮肤保护、抗炎治疗、神经退行性疾病的抑制作用以及其他在人类或兽药中的治疗潜力方面的实际应用。
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Ectoine as a promising protective agent in humans and animals
Abstract Ectoine is a compatible water molecule-binding solute (osmoprotectant) produced by several bacterial species in response to osmotic stress and unfavourable environmental conditions. This amino acid derivative can accumulate inside cells at high concentrations without interfering with natural processes and can protect the cell against radiation or osmotic stress. This brief review presents the current state of knowledge about the effects of ectoine on animals and focuses on its practical use for enzyme stabilisation, human skin protection, anti-inflammatory treatment, inhibitory effects in neurodegenerative diseases, and other therapeutic potential in human or veterinary medicine.
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