猫感染性腹膜炎(fip)的形态、临床及临床旁特征

March 16 Pub Date : 2023-07-17 DOI:10.46909/alse-561089
V. Boghian
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引用次数: 0

摘要

考虑到FIP的症状有时是非特征性的、多样的,而且往往与其他疾病的症状相似,本研究旨在确定FIP诊断中有用的形态临床和临床旁因素。对32例诊断为FIP的患者的形态学和临床特征进行了评价。26例(81.25%)患者的主要症状相似:间歇性发热、食欲不振、虚弱、呼吸困难和腹膜积液体征。腹膜穿刺液呈炎性,有大量的大吞噬细胞(中性粒细胞和巨噬细胞)、淋巴细胞,在某些情况下还有红细胞。细胞血细胞计数(CBC)显示存在正常细胞、低色素和发育不良贫血以及活跃的全身性炎症过程,在染色涂片May Grunwald Giemsa (MGG)中证实了血小板聚集和分节和空泡中性粒细胞的存在。血液生化检查显示肝细胞溶解,组织分解代谢增加和溶血性贫血的生理病理综合征的演变。这些结果证实FIP通常是一种具有多形态临床体征的全身性疾病,与CBC不同,血液生化检查具有更大的预后价值,对该病的怀疑价值较低。然而,有时单个器官的病变和相关临床症状占主导地位。因此,3例(9.37%)患者的主要症状是肝消化伴肝细胞性黄疸;1例患者有明显的肾功能衰竭临床症状,1例患者有皮质综合征症状,1例患者有骨膜病变(肉芽肿性骨炎)。这些结果表明,一些不常见的猫病变,如肉芽肿性骨炎,应列入FIP病变清单。
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MORPHOCLINICAL AND PARACLINICAL FEATURES OF FELINE INFECTIOUS PERITONITIS (FIP)
The study aims to identify the morphoclinical and paraclinical elements useful in the diagnosis of FIP, given that the symptoms are sometimes uncharacteristic, varied and often similar to those of other diseases. The morphoclinical features of 32 patients diagnosed with FIP were evaluated. In 26 patients (81.25%), the predominant symptomatology was similar: intermittent fever, loss of appetite, weakness, dyspnoea and physical signs of peritoneal fluid collection. The peritoneal puncture fluid was inflammatory, with numerous large phagocytes (neutrophils and macrophages), lymphocytes and, in some cases, red blood cells. The cell blood count (CBC) showed the existence of normocytic, hypochromic and hypoplastic anaemia and the presence of an active systemic inflammatory process, confirmed by the presence of aggregated platelets and segmented and vacuolated neutrophils in the stained smear May Grunwald Giemsa (MGG). Biochemical blood examination revealed the evolution of a physiopathological syndrome of hepatocytolysis, increased tissue catabolism and haemolytic anaemia. These results confirm that FIP is usually a systemic disease with polymorphic clinical signs, and biochemical blood tests, unlike CBC, have more prognostic value and lower value for suspecting the disease. However, sometimes, lesions and associated clinical signs in a single organ predominate. Thus, in three patients (9.37%), the predominant symptomatology was hepato-digestive with hepatocellular jaundice; one patient had obvious clinical signs of renal failure, one had signs of cortical syndrome, and one patient showed periosteal lesions (granulomatous osteitis). These results indicate that some less common lesions in cats, such as osteitis granulomatous, should be included in the list of FIP lesions.
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