Chaotic peak propagation in patients with Jackhammer esophagus

The contractile activity of Jackhammer esophagus(JE) is heterogeneous and abnormalities in the balance of pre‐ and post‐peak contractile activity has been reported. We observed that the progression of the peak contraction is disordered in JE patients, which reflect underlying abnormalities in the inhibitory and excitatory influence in esophageal contraction. In order to better define this abnormality, we developed novel time metrics to define trajectory of the pressure wave peak and assessed it in healthy controls and JE patients.