A. Murzakhmetova, V. Kemaikin, A. Ainabay, A. Meiramova, B. Ainabekova
{"title":"急性白血病患者造血干细胞移植后的急性肾病:一系列临床病例","authors":"A. Murzakhmetova, V. Kemaikin, A. Ainabay, A. Meiramova, B. Ainabekova","doi":"10.52532/2521-6414-2022-3-65-32-36","DOIUrl":null,"url":null,"abstract":"Relevance: Acute renal kidney disorder is a serious complication in patients with acute leukemia who underwent hematopoietic stem cell \ntransplantation (HSCT). According to statistics, acute renal dysfunction often occurs in the first 100 days after HSCT. \nThis study aimed to evaluate kidney function in patients with acute leukemia after hematopoietic stem cell transplantation. \nMethods: The article presents clinical cases of patients with acute lymphoblastic leukemia who developed acute renal failure after HSCT. The \ndynamics of the functional state of kidneys in patients with acute lymphoblastic leukemia after HSCT are described. \nResults: The acute kidney disorder in the studied patients was mainly caused by HSCT complications. We have identified renal kidney damage \nin the form of acute tumor lysis and thrombotic microangiopathy. \nConclusion: Patients with acute lymphoblastic leukemia risk developing acute kidney disorder during HSCT, which requires careful monitoring of kidney function, especially in the early post-transplant period.","PeriodicalId":19480,"journal":{"name":"Oncologia i radiologia Kazakhstana","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ACUTE RENAL DISORDER IN PATIENTS WITH ACUTE LEUKEMIA \\nAFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION: \\nA SERIES OF CLINICAL CASES\",\"authors\":\"A. Murzakhmetova, V. Kemaikin, A. Ainabay, A. Meiramova, B. Ainabekova\",\"doi\":\"10.52532/2521-6414-2022-3-65-32-36\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Relevance: Acute renal kidney disorder is a serious complication in patients with acute leukemia who underwent hematopoietic stem cell \\ntransplantation (HSCT). According to statistics, acute renal dysfunction often occurs in the first 100 days after HSCT. \\nThis study aimed to evaluate kidney function in patients with acute leukemia after hematopoietic stem cell transplantation. \\nMethods: The article presents clinical cases of patients with acute lymphoblastic leukemia who developed acute renal failure after HSCT. The \\ndynamics of the functional state of kidneys in patients with acute lymphoblastic leukemia after HSCT are described. \\nResults: The acute kidney disorder in the studied patients was mainly caused by HSCT complications. We have identified renal kidney damage \\nin the form of acute tumor lysis and thrombotic microangiopathy. \\nConclusion: Patients with acute lymphoblastic leukemia risk developing acute kidney disorder during HSCT, which requires careful monitoring of kidney function, especially in the early post-transplant period.\",\"PeriodicalId\":19480,\"journal\":{\"name\":\"Oncologia i radiologia Kazakhstana\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oncologia i radiologia Kazakhstana\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52532/2521-6414-2022-3-65-32-36\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oncologia i radiologia Kazakhstana","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52532/2521-6414-2022-3-65-32-36","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ACUTE RENAL DISORDER IN PATIENTS WITH ACUTE LEUKEMIA
AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION:
A SERIES OF CLINICAL CASES
Relevance: Acute renal kidney disorder is a serious complication in patients with acute leukemia who underwent hematopoietic stem cell
transplantation (HSCT). According to statistics, acute renal dysfunction often occurs in the first 100 days after HSCT.
This study aimed to evaluate kidney function in patients with acute leukemia after hematopoietic stem cell transplantation.
Methods: The article presents clinical cases of patients with acute lymphoblastic leukemia who developed acute renal failure after HSCT. The
dynamics of the functional state of kidneys in patients with acute lymphoblastic leukemia after HSCT are described.
Results: The acute kidney disorder in the studied patients was mainly caused by HSCT complications. We have identified renal kidney damage
in the form of acute tumor lysis and thrombotic microangiopathy.
Conclusion: Patients with acute lymphoblastic leukemia risk developing acute kidney disorder during HSCT, which requires careful monitoring of kidney function, especially in the early post-transplant period.