Mitigation of the biosafety risks of SARS-CoV-2 at BSL-3 laboratories

Aim: The aim of this study is to reduce the biosafety risks of laboratory exhaust air due to SARS-CoV-2 at a biosafety level-3 laboratory used for vaccine development against COVID-19 pandemic. Materials and Methods: In this study, the infrastructure and the organisation of the containment laboratory, which aimed to be used to struggle with pandemic, was used for risk assessment. Assessment of the laboratory exhaust air procedure as a component of the heating-ventilation-air conditioning system, which is significant for high-level biosafety laboratories, was conducted through a risk assessment matrix.