利用明亮的红移生物发光报告蛋白对细胞外囊泡介导的转移进行体内外分析(Advanced Genetics 1/03)

Gloria I. Perez, David Broadbent, Ahmed A. Zarea, Benedikt Dolgikh, Matthew P. Bernard, Alicia Withrow, Amelia McGill, Victoria Toomajian, Lukose K. Thampy, Jack Harkema, Joel R. Walker, Thomas A. Kirkland, Michael H. Bachmann, Jens Schmidt, Masamitsu Kanada
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引用次数: 0

摘要

细胞外囊泡成像癌细胞来源的细胞外囊泡(EVs)促进肿瘤生长和扩散。研究ev在体内的分布是了解癌症进展和开发治疗方法的关键。在文章2100055中,Masamitsu Kanada及其同事开发了一种高灵敏度的EV报告器,用于跟踪活小鼠癌细胞释放的异种EV群体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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In Vitro and In Vivo Analysis of Extracellular Vesicle-Mediated Metastasis Using a Bright, Red-Shifted Bioluminescent Reporter Protein (Advanced Genetics 1/03)

Extracellular Vesicle Imaging

Cancer cell-derived extracellular vesicles (EVs) promote tumor growth and spread. Studying the distribution of EVs in the body is key to understanding cancer progression and developing therapies. In article number 2100055, Masamitsu Kanada and co-workers develop a highly sensitive EV reporter for tracking heterogeneous EV populations released from cancer cells in live mice.

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