面部皮肤癌:一般信息和治疗方法综述

H. Witmanowski, E. Lewandowicz, Daria Sobieszek, J. Rykala, Magdalena Łuczkowska
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引用次数: 4

摘要

皮肤恶性肿瘤是人类最常见的癌症。其中,面部皮肤癌占相当大的比例。近年来,发病率急剧上升。它们的特点是局部侵袭性,它们渗入周围组织,破坏邻近结构并导致其严重丧失,这是一个严重的治疗问题,因为它们在发展的晚期被报道,手术后会造成大面积的损失,破坏面部的美观和功能。最常见的肿瘤是基底细胞癌(BCC),其次是鳞状细胞癌(SCC)。在现有的文献中,没有关于这类癌症的治疗标准的明确信息,这使得我们试图提供关于面部皮肤癌的基本信息,它们的形态学和组织学形式,以及根据位置的常规治疗。目的:本文介绍了目前关于面部非黑色素瘤癌的知识,根据原发病变位置的算法以及相关的治疗选择。它还提出了组织缺损重建的可能性,这取决于改变的位置,根据在罗兹医科大学整形、重建和美容外科治疗的选定患者。材料和方法:1998-2008年,在罗兹医科大学整形、重建和美容外科诊所,398例患者因非黑色素瘤皮肤癌接受了治疗。结果:手术治疗方法与肿瘤类型、分期及部位有关。对于位于面部的变化,在T1 (T1N0M0)的进展中,引入局部塑料手术切除,在其他情况下,应用局部皮瓣或皮肤移植。结论:尽管医学取得了巨大的进步,手术仍然是治疗面部肿瘤的首选方法。只有初次切割和合适的整形手术技术,为每个病人单独选择提供满意的结果。
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Original papers Facial skin cancers: general information and an overview of treatment methods
Introduction: Malignant tumors of the skin are the most common human cancers. Among them facial skin cancers form a sizable group. In recent years there has been a dynamic increase in morbidity. They are characterized by local invasiveness, they infiltrate the surrounding tissues, destroy adjacent structures and lead to significant loss of tis sue, which represent a serious therapeutic problem as they are reported in advanced stages of development, and after surgery there are extensive losses of disrupting the aesthetics and function of the face. The most common tumor is basal-cell carcinoma (BCC), another is squamous cell carcinoma (SCC). In available bibliography there is no clear information about the standards of treatment of this type of cancer is observed, which led us to try to pre sent basic information about facial skin cancers, their morphological and histological forms, and the routine treat ment depending on location. Aim: The paper presents the current knowledge on non-melanoma cancers of the face, the algorithm according to the primary lesion location and the related therapeutic options. It also presents the possibility of reconstruction of tissue defects, depending on the location of the change on the basis of selected patients treated at the Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Lodz. Material and methods: In the Clinic of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Lodz in the years 1998-2008, 398 patients were treated because of non-melanoma skin cancers. Results: The method of surgical treatment depended on the type of cancer, its stage and location. In the case of changes located on the face, in the advancement of T1 (T1N0M0), a surgical excision with local plastics was intro duced, in other cases – local flaps or skin grafts was applied. Conclusions: Despite enormous progress in medical science, surgery remains the method of choice in treating facial cancers. Only the primary cut and the suitable technique of plastic surgery, selected individually for each patient provides satisfactory results.
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