高脂饮食和耐力训练对近热中性小鼠腹股沟脂肪组织Sarco/内质网ATPase2 (SERCA2)和Ryanodine Receptor2 (RYR2)基因表达的影响

S. Daneshyar, A. Khosravi, Yazdan Fourotan
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摘要

结果显示,HFD、ET和HFD-ET对SERCA2a、SERCA2b和RYR2基因的相对表达量无显著影响(P>0.05)。讨论与结论:HFD和ET未改变近热中性条件下米色脂肪组织中无用钙循环的调节蛋白。因此,推测由这些条件诱导的非寒颤产热可能独立于无效循环钙发生。
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Effect of High Fat Diet and Endurance Training on the Gene Expression of Sarco/Endoplasmic Reticulum ATPase2 (SERCA2) and Ryanodine Receptor2 (RYR2) under Near-Thermoneutrality in Inguinal Adipose Tissue of Mice
showed that the relative gene expression of SERCA2a, SERCA2b, and RYR2 were not significantly affected by HFD, ET, and HFD-ET (P>0.05). Discussion & Conclusion: The HFD and ET did not change the regulatory proteins of the futile-calcium-cycle under near-thermoneutrality in the beige adipose tissue. Therefore, it was speculated that the non-shivering thermogenesis that is induced by these conditions might occur independently of futile-cycle-calcium.
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