传统眼内给药系统:展望

Gnana Prakash
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引用次数: 1

摘要

人体内最敏感、最复杂的器官是眼睛,因此给药时应特别注意进入眼睛的药物。这是研究人员在制备给眼药物过程中最困难的问题之一。给药时应考虑眼的解剖特点和生理特性。药物剂型的性质取决于眼睛的解剖和生理。将药物输送到眼部结构的外部和内部是一种独特而具有挑战性的治疗方法。物理化学,微生物学和药学性质导致活性治疗剂进入和离开眼睛的吸收和消除。常规剂型眼部给药的缺点之一是由于眼外区域的引流导致角膜前膜的快速流失。为了克服这些问题,传统剂型得到了改进。
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Conventional Opthalamic Drug Delivery System: An Outlook
The most sensitive and complex organ in the human body is the eye, so special attention should be needed for the administration of pharmaceutical substances into the eye. It is one of the most difficult for researchers in the preparation of drug delivery to the eye. The anatomical characteristics and physiological properties of the eye should be considered in drug delivery. The properties of pharmaceutical dosage forms depend upon the anatomy and physiology of the eye. Drug delivery on to the outer part as well as in the inner part of the ocular structure for the therapy is a unique and challenging one. Physiochemical, microbiological, and pharmaceutical properties lead to absorption and elimination of active therapeutic agents into and out of the eye. Loss of precorneal more and fastly occurs due to drainage in the region of extraocular are some of the drawbacks in ocular drug delivery of conventional dosage forms. To overcome these problems, advancements in conventional dosage forms take place.
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