{"title":"黄腐酸功能性滋养霜的研制","authors":"B. Jo, Jun-Ho Jo, Y. Lee","doi":"10.9790/3008-1203034758","DOIUrl":null,"url":null,"abstract":"Fulvic acid is a natural material contained within soil that contains an ample amount of minerals and various functionalities such as antioxidation, currently making it a popular choice as a raw material for food, medicine and cosmetic products. Therefore, the research is to develop functional cosmetics for the prevention of skin aging by using fulvic acid, a natural humic substance that is effective in improving whitening and wrinkle. However, adenosine, edelweiss-cultured natural extracts, Niacinamide, Bio-AHP 500H, etc. are mixed in the cream to minimize the effective chelate reaction. Also,stable production was proposed including weight-measuring scale, stirring AGi adjustment and etc. that are performed for a smooth chelate reaction of crude fulvic acid solution. Furthermore, various tests such as including a skin cell safety test, collagen synthesis test, wrinkle improvement-related gene expression analysis test, anti-aging and antioxidative effect test and melanin synthesis inhibition test are performed and showed an outstanding level of performance in all tests. Finally, the cream has been tested on 5 items, criteria of quality assessment in cosmetic testing by the Ministry of Food & Drug safety, which are lead, arsenic, mercury, methanol, etc. and have passed all the inspection criteria.","PeriodicalId":14548,"journal":{"name":"IOSR Journal of Pharmacy and Biological Sciences","volume":"405 1","pages":"47-58"},"PeriodicalIF":0.0000,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Development of functional nourishing cream using fulvic acid\",\"authors\":\"B. Jo, Jun-Ho Jo, Y. Lee\",\"doi\":\"10.9790/3008-1203034758\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Fulvic acid is a natural material contained within soil that contains an ample amount of minerals and various functionalities such as antioxidation, currently making it a popular choice as a raw material for food, medicine and cosmetic products. Therefore, the research is to develop functional cosmetics for the prevention of skin aging by using fulvic acid, a natural humic substance that is effective in improving whitening and wrinkle. However, adenosine, edelweiss-cultured natural extracts, Niacinamide, Bio-AHP 500H, etc. are mixed in the cream to minimize the effective chelate reaction. Also,stable production was proposed including weight-measuring scale, stirring AGi adjustment and etc. that are performed for a smooth chelate reaction of crude fulvic acid solution. Furthermore, various tests such as including a skin cell safety test, collagen synthesis test, wrinkle improvement-related gene expression analysis test, anti-aging and antioxidative effect test and melanin synthesis inhibition test are performed and showed an outstanding level of performance in all tests. Finally, the cream has been tested on 5 items, criteria of quality assessment in cosmetic testing by the Ministry of Food & Drug safety, which are lead, arsenic, mercury, methanol, etc. and have passed all the inspection criteria.\",\"PeriodicalId\":14548,\"journal\":{\"name\":\"IOSR Journal of Pharmacy and Biological Sciences\",\"volume\":\"405 1\",\"pages\":\"47-58\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IOSR Journal of Pharmacy and Biological Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9790/3008-1203034758\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IOSR Journal of Pharmacy and Biological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9790/3008-1203034758","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Development of functional nourishing cream using fulvic acid
Fulvic acid is a natural material contained within soil that contains an ample amount of minerals and various functionalities such as antioxidation, currently making it a popular choice as a raw material for food, medicine and cosmetic products. Therefore, the research is to develop functional cosmetics for the prevention of skin aging by using fulvic acid, a natural humic substance that is effective in improving whitening and wrinkle. However, adenosine, edelweiss-cultured natural extracts, Niacinamide, Bio-AHP 500H, etc. are mixed in the cream to minimize the effective chelate reaction. Also,stable production was proposed including weight-measuring scale, stirring AGi adjustment and etc. that are performed for a smooth chelate reaction of crude fulvic acid solution. Furthermore, various tests such as including a skin cell safety test, collagen synthesis test, wrinkle improvement-related gene expression analysis test, anti-aging and antioxidative effect test and melanin synthesis inhibition test are performed and showed an outstanding level of performance in all tests. Finally, the cream has been tested on 5 items, criteria of quality assessment in cosmetic testing by the Ministry of Food & Drug safety, which are lead, arsenic, mercury, methanol, etc. and have passed all the inspection criteria.