一项评估三级保健医院孕妇COVID-19感染结局的前瞻性队列研究

M. Choudhury, Sivaji Ghose, G. Maiti
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摘要

背景:全球范围内的COVID-19感染造成了严重破坏。本研究中新冠病毒阳性孕妇的数量与全国平均水平相差不远。本研究旨在评估孕妇在产前、产中和产后感染COVID-19的结果。方法学:研究设计为前瞻性队列研究。2020年3月至2021年6月,该三级保健医院收治的2019冠状病毒病妊娠患者总数为106例,处于不同孕期。这家医院的服务对象是现役人员、退役军人和印度武装部队的家属。所研究的群体只是家属和在职女性工作人员。适当的病史、主诊、妊娠期、产科和全身检查结果、症状严重程度、家庭隔离或住院以及治疗情况均以问卷的形式记录下来。最后,对这些新冠病毒阳性孕妇的产前、产时、产后和新生儿结局进行汇总和研究。结果:被调查社区新冠病毒阳性孕妇患病率为9.9%。约43.39%的病例在妊娠晚期确诊。在本研究中,93%的患者无症状或症状非常轻微。本组分娩方式以剖宫产为主(69.56%)。结论:本研究中妊娠相关并发症发生率在2.8% ~ 3%之间,仅有2例新生儿为COVID阳性。
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A prospective cohort study to evaluate the outcome of COVID-19 infection in pregnant women in a tertiary care hospital
Background: Worldwide COVID-19 infection has played havoc. The number of COVID-positive pregnant cases in this study was not far behind the National average. The present study was conducted to evaluate the outcome of COVID-19 infection in pregnant women during their antenatal, intrapartum, and postnatal periods. Methodology: The study design was a prospective cohort study. The total number of COVID-19 pregnant patients admitted to this tertiary care hospital from March 2020 to June 2021 was 106 cases at various trimesters. This hospital caters to serving personnel, ex-servicemen, and dependents of the Indian Armed Forces. The community being studied were only the dependents and the serving female personnel. Proper history, presenting complaints, period of gestation, obstetric and systemic examination findings, the severity of symptoms, home isolation or hospital stay, and treatment were all recorded in the form of the questionnaire. Finally, the antenatal, intrapartum, postnatal, and neonatal outcomes of these COVID-positive pregnant patients were compiled and studied. Results: The prevalence of COVID-positive pregnant women in the community being studied was 9.9%. About 43.39% of the cases were diagnosed in the third trimester. Ninety-three percent of the patients in the present study were asymptomatic or with very mild symptoms. The mode of delivery in the present study was mostly by cesarean section (69.56%). Conclusion: In the present study, pregnancy-associated complications were within the range of 2.8%–3% and only two newborns were COVID positive.
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