儿童神经发育和行为问题是相互关联的,在一般人群中具有维度分布

H. Anckarsäter, T. Larson, S. Hansson, E. Carlström, O. Ståhlberg, C. Gillberg, M. Råstam, C. Gillberg, P. Lichtenstein
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引用次数: 27

摘要

自闭症-抽动、AD/HD和其他共病量表(a - tac)是一项全面的访谈,用于评估儿童和青少年中与自闭症谱系障碍(ASD)、抽动障碍、注意力缺陷/多动障碍(AD/HD)和常见合并症相关的问题。A-TAC对2957名9岁或12岁儿童的父母进行了电话访谈,这些儿童代表瑞典儿童和青少年双胞胎研究(CATSS)中每对双胞胎中的一个。共有16.4%的人在一种或几种目标疾病中呈筛查阳性,ASD为1.3%,AD/HD为5.6%。除了与“饮食习惯”有关的问题外,所有类型的问题在男孩中都更为常见。它们都是维度/连续分布的,高度相互关联的,跨类型重叠的。这些问题归结为三个基本因素,分别是外化/破坏性、社会交际问题和强迫性。因此,基于人口的儿童问题数据挑战了目前的分类诊断定义,要求问题描述的维度和互补模型。
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Child Neurodevelopmental and Behavioural Problems are Intercorrelated and Dimensionally Distributed in the General Population
The Autism - Tics, AD/HD, and other Comorbidities inventory (A-TAC) is a comprehensive interview for evaluating problems related to autism spectrum disorders (ASD), tic disorders, attention-deficit/hyperactivity disorder (AD/HD), and common comorbid conditions in children and adolescents. A-TAC telephone interviews were administered to parents of 2,957 children aged nine- or twelve-years, representing one in each twin pair included in the population- based Child and Adolescent Twin Study in Sweden (CATSS). A total of 16.4% were screen-positive for one or several of the targeted disorder, 1.3% for ASD and 5.6% for AD/HD. All types of problems were more common among boys, with the exception of those related to "eating habits". They were all dimensionally/continuously distributed, highly inter-correlated, and overlapped across types. They aggregated in three ba- sic factors corresponding to externalizing/disruptiveness, socio-communicative problems, and compulsiveness. Population-based data on problems in children thus challenge current categorical diagnostic definitions, calling for dimen- sional and complementary models of problem descriptions.
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