增强疫苗剂量和单克隆抗体存在下抗体中和组粒变异的增强作用

A. Dawood
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引用次数: 0

摘要

欧米克隆变种正迅速成为在世界各地传播的最常见的SARS-CoV-2病毒。为了了解对欧米克隆感染的保护可能丧失,确定恢复期或接种疫苗者血清中病毒中和活性的下降是至关重要的。科学家们已经发现了针对欧米克隆和各种变体的抗体。这些抗体针对病毒刺突蛋白的非进化区域。加强剂量可以提高体液免疫反应的质量和数量,这与更好地预防疾病更严重的症状有关。必须在世界各地迅速提供疫苗和增强剂,以阻止病毒的传播。
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Enhancement of Antibodies Neutralize Omicron variants in The Presence of Booster Vaccine Doses and Monoclonal Antibodies
The Omicron variant is quickly becoming the most common SARS-CoV-2 virus spreading throughout the world. To understand probable loss of protection against Omicron infection, it's critical to identify declines in viral neutralizing activity in serum of convalescent or vaccinated people. Antibodies against Omicron and various variants have been detected by scientists. These antibodies target non-evolving regions of the viral spike protein. A booster dose improves the quality and amount of the humoral immune response, which has been related to better protection against the disease's more severe signs. Vaccines and boosters must be provided promptly around the world to stop the virus from spreading.
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