伤寒儿科住院患者临床症状、实验室及抗生素治疗

R. Rayhana, L. S. Hernawan
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摘要

伤寒的临床特征从轻微到严重不等。印度尼西亚的伤寒实验室检查仍然使用维达尔试验作为诊断工具。1992年,伤寒沙门氏菌的分离株显示出对氟喹诺酮类药物的耐药性,第一例报告发生在联合王国。包括印度在内的其他几个国家也报告了类似的病例。本研究旨在描述2017年1月至3月在西爪哇省X医院住院的伤寒儿童的临床症状、实验室和抗生素使用情况。本研究为描述性回顾性研究,采用横断面设计,共有127名受访者。该研究于2018年1月至3月进行。在西爪哇X医院住院的伤寒患者中,年龄在5-9岁之间的占37%,其中男性占51.18%,住院时间为3天的占29.13%。维达尔滴度O阳性占13.91%,H阳性占45.21%,管状阳性占93.75%,白细胞减少占26.77%,Hb值<11.5占48.81%,患者发热占99.21%,85.03%给予头孢曲松治疗。伤寒儿童常出现的临床症状是发烧,通常给予的抗生素是头孢曲松。关键词:伤寒,维达尔滴度,耐药性
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Typhoid Pediatric Inpatient Clinical Symptoms, Laboratory and Antibiotic Treatment
Clinical features of typhoid fever vary from mild to severe. Laboratory examination for typhoid fever in Indonesia still uses the Widal test as a diagnostic tool. In 1992, isolates of S.typhi showed resistance to fluoroquinolones, with the first case reported in the United Kingdom. Similar cases were reported from several other countries, including India. This study aimed to describe the clinical symptoms, laboratory and antibiotics used for children with typhoid hospitalized at Hospital ‘X’ in West Java from January to March 2017. This research was a descriptive retrospective, using a cross-sectional design with a total sample of 127 respondents. The study was conducted from January to March 2018. Patients suffering from typhoid were hospitalized at Hospital ‘X’, West Java, were 37% aged between 5-9 years old with 51.18% males and those whose length of stay was for 3 days was 29.13%. Widal Titer O positive examination was 13.91% and positive H Titer was 45.21%, positive tubex 93.75%, 26.77% leukopenia, 48.81% with Hb value <11.5, the patient had a fever of 99.21%, 85.03% was given ceftriaxone. Clinical symptoms that are often experienced by children with typhoid typhoid is fever and the antibiotics that are often given are ceftriaxone. Keywords: typhoid fever, widal titer, resistance
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