血清总前列腺特异性抗原和游离前列腺特异性抗原水平作为新冠肺炎患者的生物标志物

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摘要

目的:评价TPSA和FPSA在COVID-19早期检测中的诊断价值,并与对照组进行比较。方法:对来自塞卜哈市呼吸诊所的146例患者进行回顾性研究,其中73例经pcr确诊为COVID-19, 73例未感染COVID-19(对照组)。结果:pcr确诊组平均年龄为61.51±16.40岁。在pcr确诊的COVID-19组中,TPSA的平均和标准划分血清生物标志物水平为0.51±。26 ng/ml, FPSA 0.57±0.32。结论:在生物标志物TPSA和FPSA方面,对照组与pcr确诊的COVID-19组之间无显著差异。这些发现表明,肿瘤生物标志物可能对COVID-19检测无效。
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Serum Total and Free Prostate Specific Antigen Levels as Novel Biomarker in Patients with COVID-19
Objectives: This study aimed to evaluate the diagnostic value of TPSA and FPSA for early detection of COVID-19 and compare it with a control group. Methods: This is a retrospective study of 146 patients from the Respiratory Clinic in Sebha city, 73 of whom have COVID-19 PCR-confirmed and 73 who do not have COVID-19 (group control). Results: The mean and standard division age in the PCR-confirmed COVID-19 group was 61.51±16.40. In the PCR-confirmed COVID-19 group, the mean and standard division serum biomarker level for TPSA was 0.51±.26 ng/ml, and 0.57± 0.32 for FPSA. Conclusion: For the biomarkers TPSA and FPSA, there were no significant differences between the control and PCR-confirmed COVID-19 groups. These findings suggest that the tumor biomarker may be ineffective in detecting COVID-19.
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