{"title":"一锅三组分法合成几种新型吡唑啉类化合物及其相应的噻唑类化合物","authors":"R. H. H. Salih, F. Hawaiz","doi":"10.24271/GARMIAN.159","DOIUrl":null,"url":null,"abstract":"In the present study; a one-pot three component reaction between4(4'-chlorobenzyloxy)acetophenone , thiosemicarbazide and different substituted benzaldehydes in absolute ethanolunder reflux with stirring has been used to give a new series of pyrazoline derivatives {3-(4-[4'-chlorobenzyloxy)phenyl)-5-(substituted-phenyl]-4,5-dihydropyrazole-1-carbothioamide}in highyields and short reaction times. . The later compounds were converted to their correspondingthiazole derivatives through reacting with 4-bromophenacyl bromide in ethanol. , The structures of the newly synthesized compounds were identified on the bases of their FT-IR, 1H-NMR, 13C-NMR and DEPT-135 spectra.","PeriodicalId":12283,"journal":{"name":"Evaluation Study of Three Diagnostic Methods for Helicobacter pylori Infection","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Synthesis of Some New Pyrazolines via One-Pot Three Component Technique and Their Corresponding Thiazole Compounds\",\"authors\":\"R. H. H. Salih, F. Hawaiz\",\"doi\":\"10.24271/GARMIAN.159\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the present study; a one-pot three component reaction between4(4'-chlorobenzyloxy)acetophenone , thiosemicarbazide and different substituted benzaldehydes in absolute ethanolunder reflux with stirring has been used to give a new series of pyrazoline derivatives {3-(4-[4'-chlorobenzyloxy)phenyl)-5-(substituted-phenyl]-4,5-dihydropyrazole-1-carbothioamide}in highyields and short reaction times. . The later compounds were converted to their correspondingthiazole derivatives through reacting with 4-bromophenacyl bromide in ethanol. , The structures of the newly synthesized compounds were identified on the bases of their FT-IR, 1H-NMR, 13C-NMR and DEPT-135 spectra.\",\"PeriodicalId\":12283,\"journal\":{\"name\":\"Evaluation Study of Three Diagnostic Methods for Helicobacter pylori Infection\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Evaluation Study of Three Diagnostic Methods for Helicobacter pylori Infection\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24271/GARMIAN.159\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Evaluation Study of Three Diagnostic Methods for Helicobacter pylori Infection","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24271/GARMIAN.159","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Synthesis of Some New Pyrazolines via One-Pot Three Component Technique and Their Corresponding Thiazole Compounds
In the present study; a one-pot three component reaction between4(4'-chlorobenzyloxy)acetophenone , thiosemicarbazide and different substituted benzaldehydes in absolute ethanolunder reflux with stirring has been used to give a new series of pyrazoline derivatives {3-(4-[4'-chlorobenzyloxy)phenyl)-5-(substituted-phenyl]-4,5-dihydropyrazole-1-carbothioamide}in highyields and short reaction times. . The later compounds were converted to their correspondingthiazole derivatives through reacting with 4-bromophenacyl bromide in ethanol. , The structures of the newly synthesized compounds were identified on the bases of their FT-IR, 1H-NMR, 13C-NMR and DEPT-135 spectra.