凝集素:简要回顾

G. P. Espino-Solís
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引用次数: 2

摘要

由于植物凝集素具有区分不同血型红细胞的能力,Boyd和Shapleigh(1954)为其提出了“lectins”的名称,源自拉丁语“legere”,意为“挑选”或“选择”[1]。该术语后来被推广到包括所有非免疫来源的糖特异性凝集素,而不考虑其来源和血型特异性[2]。直到19世纪末,有关自然界中存在具有凝集红细胞能力的蛋白质的证据才首次开始积累。这种蛋白质被称为血凝素或植物凝集素,因为它们最初是在植物提取物中发现的。
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LECTINS: A BRIEF REVIEW
The ability of plant agglutinins to distinguish between erythrocytes of different blood types led Boyd and Shapleigh (1954) to propose for them the name lectins, from the Latin “legere”, to pick out or choose [1]. This term was later generalized to embrace all sugar-specific agglutinins of non-immune origin, irrespective of source and blood type specificity [2]. It was toward the end of the 19th century that evidence first started to accumulate for the presence in nature of proteins possessing the ability to agglutinate erythrocytes. Such proteins were referred to as hemagglutinins, or phytoagglutinins, because they were originally found in extracts of plants…
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