本中心首批50例Sars-Cov-2阳性患者的妊娠结局

M. Dey, Sanjay Singh, R. Tiwari, V. Nair, D. Arora, S. Tiwari
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引用次数: 14

摘要

目的:妊娠期免疫系统的抑制和生理变化使孕妇易患各种病毒性疾病。多项研究报告了SARS-CoV-2感染的不良妊娠结局。本研究旨在评估在我们的设置中受SARS-CoV-2影响的妊娠的母胎结局。研究设计:这是一项在印度陆军三级医院进行的前瞻性队列研究。本研究纳入了2020年4月1日至2020年9月15日期间在独立机构接收和管理的首批50例SARS-CoV-2阳性孕妇和144例SARS-CoV-2阴性疑似病例。比较她们的产科和新生儿结局以及人口统计学和其他临床数据。结果:孕妇SARS-CoV-2感染RT-PCR总阳性率为2.7%。96%的患者无SARS-CoV-2感染症状。两组的胎膜早破、早产和入住新生儿重症监护病房的情况相似。SARS-CoV-2阳性孕妇剖宫产率增加(70%)。结论:该研究报告了与SARS-CoV-2阴性孕妇相比,SARS-CoV-2阳性孕妇的母婴结局具有可比性。
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Pregnancy Outcome in First 50 Sars-Cov-2 Positive Patients At Our Center
OBJECTIVES: Suppressed immune system and physiological changes in pregnancy put pregnant women vulnerable to various viral diseases. Various studies have reported adverse pregnancy outcomes in SARS-CoV-2 infection. This study aimed to evaluate the maternal and fetal outcomes in SARS-CoV-2 affected pregnancies at our set up. STUDY DESIGN: It was a prospective cohort study conducted at a tertiary care Army Hospital, India. The first 50 cases of SARS CoV-2 positive pregnant women and 144 suspected cases that were found SARS-CoV-2 negative, received and managed at separate set up, during a period extending from 01 April 2020 to 15 Sep 2020 were included in our study. Their obstetric and neonatal outcomes along with the demographic and other clinical data were compared. RESULTS: Total RT-PCR positivity rate of SARS-CoV-2 infection in pregnant women was 2.7%. 96% of our patients were asymptomatic for SARS-CoV-2 infection. Premature rupture of membrane, preterm delivery, and NICU admission was similar in both groups. There were increased incidences (70%) of cesarean section in SARS-CoV-2 positive pregnant women. CONCLUSION: The study reported comparable maternal and fetal outcomes in SARS-CoV 2 positive pregnant women when compared with SARS-CoV-2 negative pregnant women.
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