Szabolcs Vígh, Z. Cziáky, L. Sinka, C. Pribac, L. Moș, V. Turcuș, J. Remenyik, E. Máthé
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Analysis of phytoconstituent profile of fenugreek –Trigonella Foenuem-graecum L. - seed extracts
Fenugreek (Trigonella foenum-graecum L.) is a well-known herb for its efficiency in the prevention/treatment of diabetes among other chronic diseases. The aim of present study was to analyse the phytoconstituent profile of aqueous and hydro-alcoholic extracts of fenugreek seeds produced in Hungary. The aqueous and hydro-aqueous extracts were analysed using a UHPLC-ESI-MS approach, and in the first 54, while in the second extract 67 phytoconstituents were identified that mostly corroborate the previously described health promoting effects of fenugreek. However, it remains a huge challenge to correlate the phytoconstituent composition of the two extracts with the generated dose dependent hormetic response and cytotoxic effects that were reported by us in case of some human breast cancerous cell lines.
期刊介绍:
Studia Universitatis Babes-Bolyai, Seria Chemia publishes fundamental studies in all areas of chemistry and chemical engineering.
Coverage includes experimental and theoretical reports on quantitative studies of structure and thermodynamics, kinetics, mechanisms of reactions, inorganic, organic, organometallic chemistry, biochemistry, computational chemistry, solid-state phenomena, surface chemistry, chemical technology and environmental chemistry.