拟南芥WEE1激酶调控DNA损伤的细胞周期阻滞

N. Eckardt
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引用次数: 7

摘要

当细胞经历DNA损伤时,共济失调毛细血管扩张突变(ATM)和rad3相关(ATR)信号激酶同时激活短暂的细胞周期阻滞并诱导DNA修复途径,使细胞在进入有丝分裂之前修复DNA。自动取款机对双-有专门的反应
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Arabidopsis WEE1 Kinase Controls Cell Cycle Arrest in Response to DNA Damage
When cells experience DNA damage, the ataxia telangiectasia–mutated (ATM) and Rad3-related (ATR) signaling kinases simultaneously activate a transient cell cycle arrest and induce DNA repair pathways, allowing cells to repair DNA before proceeding into mitosis. ATM responds specifically to double-
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