{"title":"血红素加氧酶-1与慢性阻塞性肺疾病的研究进展","authors":"Weixia Li, Jiaqiang Zhang","doi":"10.3760/CMA.J.ISSN.1673-436X.2020.02.007","DOIUrl":null,"url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) is a preventable and treatable respiratory disease characterized by persistent airflow limitation.Its mechanism has not yet been fully clarified.In recent years, many studies have shown that oxidative stress and gene polymorphism play a very important role in its development.Heme oxygenase-1 (HO-1) is an important oxygen reductase in the body and is closely related to COPD.This article reviews the relationship between the occurrence, development, treatment and prognosis of HO-1 and COPD, in order to provide new ideas for the diagnosis, treatment and management of COPD. \n \n \nKey words: \nPulmonary disease, chronic obstructive; Genes, duplicate; Heme oxygenase-1","PeriodicalId":10004,"journal":{"name":"Chinese Journal of Asthma","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Research progress of heme oxygenase-1 and chronic obstructive pulmonary disease\",\"authors\":\"Weixia Li, Jiaqiang Zhang\",\"doi\":\"10.3760/CMA.J.ISSN.1673-436X.2020.02.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chronic obstructive pulmonary disease (COPD) is a preventable and treatable respiratory disease characterized by persistent airflow limitation.Its mechanism has not yet been fully clarified.In recent years, many studies have shown that oxidative stress and gene polymorphism play a very important role in its development.Heme oxygenase-1 (HO-1) is an important oxygen reductase in the body and is closely related to COPD.This article reviews the relationship between the occurrence, development, treatment and prognosis of HO-1 and COPD, in order to provide new ideas for the diagnosis, treatment and management of COPD. \\n \\n \\nKey words: \\nPulmonary disease, chronic obstructive; Genes, duplicate; Heme oxygenase-1\",\"PeriodicalId\":10004,\"journal\":{\"name\":\"Chinese Journal of Asthma\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chinese Journal of Asthma\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1673-436X.2020.02.007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Journal of Asthma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-436X.2020.02.007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Research progress of heme oxygenase-1 and chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable respiratory disease characterized by persistent airflow limitation.Its mechanism has not yet been fully clarified.In recent years, many studies have shown that oxidative stress and gene polymorphism play a very important role in its development.Heme oxygenase-1 (HO-1) is an important oxygen reductase in the body and is closely related to COPD.This article reviews the relationship between the occurrence, development, treatment and prognosis of HO-1 and COPD, in order to provide new ideas for the diagnosis, treatment and management of COPD.
Key words:
Pulmonary disease, chronic obstructive; Genes, duplicate; Heme oxygenase-1
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