新诊断糖尿病患者高脂血症模式分析

Shazma Ansar Butt, Nasira Pervaiz, M. Mehmood
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摘要

目的:分析初诊青年糖尿病患者高脂血症的特点。研究设计:描述性横断面研究。地点和时间:研究于2017年1月和2018年1月在Nawaz Shareef医学院和拉瓦尔品第医科大学进行。方法:所有患者均为年轻、新诊断的糖尿病患者。通过非概率连续抽样收集数据,包括患者的人口统计学、既往病史、合并症,并评估实验室结果。采用SPSS version 24进行数据分析。P值≤0.05为差异有统计学意义。结果:80例患者纳入本研究。糖尿病肾病、糖尿病视网膜病变、大血管并发症、高血糖性高渗性非酮症昏迷史、家族史和高血压患者分别为n=12(15%)、n=6(7.5%)、n=9(11.3%)、n=1(1.3%)、n=34(42.5%)和n=11(13.8%)。患者平均高脂血症、高甘油三酯血症分别为4.54±0.52 mmol/L、2.59±1.13 mmol/L、1.39±0.80 mmol/L、1.03±0.59 mmol/L。结论:研究表明,在这些患者中,甘油三酯水平升高的患病率高于LDL胆固醇水平升高的患病率。由于已经确定高甘油三酯血症是引起糖尿病患者心血管疾病的已知危险因素,因此应在糖尿病发病时进行相应的处理和管理。关键词:高脂血症,糖尿病,低密度脂蛋白,高密度脂蛋白,胰岛素DOI: 10.7176/JMPB/62-08出版日期:12月31日2019
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Analysis of Hyperlipidemia Pattern in newly Diagnosed Diabetic Patients
Objective : To analyze hyperlipidemia patterns among newly diagnosed young diabetic patients. Study Design : A descriptive cross-sectional study. Place and Duration: Study was conducted in Nawaz Shareef Medical College and Rawalpindi Medical University from Jan 2017 and Jan 2018. Methodology: All the patients were young and newly diagnosed with Diabetes Mellitus. Data collection was done via non probability consecutive sampling included patients’ demographics, past medical history, co-morbidities, and lab findings were assessed. SPSS version 24 was used to analyze data. P value ≤ 0.05 was taken as significant. Results : Eighty patients were included in this study. Diabetic nephropathy, diabetic retinopathy, macrovascular complications, hyperglycemic hyperosmolar non-ketotic coma history, family history and hypertension were noted in n=12 (15%), n=6 (7.5%), n=9 (11.3%), n=1 (1.3%), n=34 (42.5%) and n=11 (13.8%) respectively. The mean hyperlipidemia, hypertriglyceridemia, of the patients was 4.54±0.52 mmol/L, 2.59±1.13 mmol/L, 1.39±0.80 mmol/L, 1.03±0.59 mmol/L respectively. Conclusion : the study has shown that the prevalence of increased levels of triglycerides is more than increased LDL cholesterol levels among these patients. As it has been established that hypertriglyceridemia is a known risk factor for causing cardiovascular disorders among diabetic patients, it should be addressed and managed accordingly at the onset of diabetes. Key words : Hyperlipidemia, Diabetes Mellitus, low density lipoproteins, high density lipoproteins, insulin. DOI : 10.7176/JMPB/62-08 Publication date: December 31 st 2019
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