S. Biletskyi, T. Kazantseva, O. Petrynych, V. Petrynych
{"title":"心血管疾病的降脂治疗(文献综述)","authors":"S. Biletskyi, T. Kazantseva, O. Petrynych, V. Petrynych","doi":"10.24061/2413-0737.xxv.4.100.2021.19","DOIUrl":null,"url":null,"abstract":"Literature data on the pathogenesis of atherosclerosis, the use of statins, ezetimibe and inhibitors of subtilisin / kexin type 9 proprotein convertase monoclonal antibodies (PCSK9) in the prevention and treatment of cardiovascular diseases have been presented.Objective - to systematize current data on the pathogenesis of atherosclerosis, the effectiveness of lipid-lowering therapy of cardiovascular diseases.Conclusion. To date, the role of dyslipidemia and inflammation in the pathogenesis of atherosclerosis, the effectiveness of statins, ezetimibe and PCSK9 inhibitors in the prevention and treatment of cardiovascular diseases have been established.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"231 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lipid-lowering therapy of cardiovascular diseases (literature review)\",\"authors\":\"S. Biletskyi, T. Kazantseva, O. Petrynych, V. Petrynych\",\"doi\":\"10.24061/2413-0737.xxv.4.100.2021.19\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Literature data on the pathogenesis of atherosclerosis, the use of statins, ezetimibe and inhibitors of subtilisin / kexin type 9 proprotein convertase monoclonal antibodies (PCSK9) in the prevention and treatment of cardiovascular diseases have been presented.Objective - to systematize current data on the pathogenesis of atherosclerosis, the effectiveness of lipid-lowering therapy of cardiovascular diseases.Conclusion. To date, the role of dyslipidemia and inflammation in the pathogenesis of atherosclerosis, the effectiveness of statins, ezetimibe and PCSK9 inhibitors in the prevention and treatment of cardiovascular diseases have been established.\",\"PeriodicalId\":9270,\"journal\":{\"name\":\"Bukovinian Medical Herald\",\"volume\":\"231 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bukovinian Medical Herald\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24061/2413-0737.xxv.4.100.2021.19\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bukovinian Medical Herald","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24061/2413-0737.xxv.4.100.2021.19","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Lipid-lowering therapy of cardiovascular diseases (literature review)
Literature data on the pathogenesis of atherosclerosis, the use of statins, ezetimibe and inhibitors of subtilisin / kexin type 9 proprotein convertase monoclonal antibodies (PCSK9) in the prevention and treatment of cardiovascular diseases have been presented.Objective - to systematize current data on the pathogenesis of atherosclerosis, the effectiveness of lipid-lowering therapy of cardiovascular diseases.Conclusion. To date, the role of dyslipidemia and inflammation in the pathogenesis of atherosclerosis, the effectiveness of statins, ezetimibe and PCSK9 inhibitors in the prevention and treatment of cardiovascular diseases have been established.
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