新型五取代环己醇对微生物的生物活性研究

IF 0.5 4区化学 Q3 Pharmacology, Toxicology and Pharmaceutics Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-02-15 DOI:10.56042/ijcb.v60i2.29657

I. Mamedov, Y. Mamedova

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引用次数: 0

摘要

芳香酮类化合物是有机合成中的有效化合物，对合成各种具有生理活性的实用化合物具有重要意义。由于其不同的功能，这些化合物赋予生物活性，如抗菌、抗菌、抗真菌、抗癌、抗病毒、抗炎、降血糖。考虑到它们的药物现状，研究了1,2,3,4,5-五取代环己醇及其形成查尔酮对金黄色葡萄球菌、大肠杆菌、克雷伯氏菌、肠杆菌、沙雷氏菌和尼日尔黑杆菌的作用。

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Biological activity of novel pentasubstituted cyclohexanol against some microorganisms

The aromatic ketones are effective compounds in organic synthesis and have important significance for synthesis of different practical compounds, which have physiological activity. Due to the their different functionality these compounds confer biological activities, such as antimicrobial, antibacterial, antifungal, anticancer, antiviral, anti-inflammatory, antihyperglycemic. Taking into account of their pharmaceutical actuality the 1,2,3,4,5-pentasubstituted cyclohexanol and its forming chalcone against S. aureus, E. coli, KES (Klebsiella, Enterobacter, Serratia) and A. niger were investigated.

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来源期刊

Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry 化学-有机化学

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Indian Journal of Chemistry (Section B) is a leading monthly journal in Organic and Medicinal Chemistry started publishing from 1976. It publishes papers on organic reaction mechanism, theoretical organic chemistry, structure-activity relationships, medicinal chemistry, synthesis of chiral compounds, bio-organic chemistry, enzymes in organic synthesis, reagents in organic synthesis, heterocyclic compounds, phytochemistry (natural products), amino acids, peptides and proteins, spectroscopy in characterization of organic compounds, chemoenzymatic and enantioselective synthesis of organic compounds, synthesis of fullerenes, metal-catalyzed asymmetric reactions, bioactive plant products and combinatorial chemistry. Apart from full length papers, notes and communications, the journal publishes short reviews on frontline areas under the column " advances in Contemporary Research".