Benjamin Sihite, M. Sitepu, K. Sukatendel, Sarma Nursani Lumbanraja, Iman Helmi Effendi, Rizki Yaznil, E. Ardiansyah
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The study was conducted at Universitas Sumatera Utara (USU) Hospital Laboratory and RSUP H. Adam Malik for 6 months, from January 2021 to June 2021. The data collected were analyzed using descriptive statistics. If the data were normally distributed, they were presented as mean + SD; otherwise, they were presented as median (min-max) for each variable. The Statistical Package for Social Sciences version 22.0 (IBM SPSS Corp.; Armonk, NY, USA) was used for statistical analysis.\nResults: Neonatal umbilical cord serology results (IgM and IgG) were predominantly non-reactive, where IgM was non-reactive in 43 neonates (97.7%) and IgG was non-reactive in 37 neonates (84.1%). In mothers without COVID-19 symptoms, neonate umbilical cord serology results were dominated by non-reactive IgM (88.6%) and IgG (79.5%). In mothers who recovered from COVID-19, neonate umbilical cord serology results were also dominated by non-reactive IgM (95.5%) and IgG (81.8%).\nConclusion: The neonatal umbilical cord serology results from the mother confirmed with positive COVID-19 were nonreactive IgG and IgM in the majority of 35 (79%) samples, reactive IgG in 7 (15.9%), and reactive IgM in 1 (2%) sample.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Serological description of neonatal umbilical cord blood from pregnant woman confirmed with positive COVID-19 by RT-PCR at Rumah Sakit Umum Pusat H. Adam Malik, Medan, Indonesia\",\"authors\":\"Benjamin Sihite, M. Sitepu, K. Sukatendel, Sarma Nursani Lumbanraja, Iman Helmi Effendi, Rizki Yaznil, E. Ardiansyah\",\"doi\":\"10.20473/mog.v30i32022.128-133\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"HIGHLIGHTS\\n1. COVID-19 raises concern in regard with its effect on pregnancy.2. The serological descriptions of umbilical cord of neonates born from mothers suffering from COVID-19 were identified.3. Most of the serology was non-reactive IgG and IgM, followed was reactive IgG and the least was the reactive IgM.\\n \\nABSTRACT\\nObjective: To evaluate the serological description of the neonatal umbilical cord in COVID-19 mothers confirmed by RT-PCR at Rumah Sakit Umum Pusat (RSUP) H. Adam Malik Medan in January-June 2021.\\nMaterials and Methods: This study was an observational study with a case series approach where the cases were mothers infected with SARS CoV-2 confirmed by RT-PCR. The study was conducted at Universitas Sumatera Utara (USU) Hospital Laboratory and RSUP H. Adam Malik for 6 months, from January 2021 to June 2021. 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引用次数: 0
摘要
HIGHLIGHTS1。COVID-19对怀孕的影响令人关切。对感染COVID-19的母亲所生的新生儿脐带进行血清学描述。血清学以无反应性IgG和IgM居多,其次为反应性IgG,反应性IgM最少。【摘要】目的:评价2021年1 - 6月亚当马利克棉兰医院(Rumah Sakit Umum Pusat, RSUP)经RT-PCR确诊的新冠肺炎母亲的新生儿脐带血清学特征。材料和方法:本研究是一项观察性研究,采用病例系列方法,病例为经RT-PCR确诊的感染SARS CoV-2的母亲。该研究于2021年1月至2021年6月在苏门答腊北方大学(USU)医院实验室和RSUP H. Adam Malik进行,为期6个月。收集的数据采用描述性统计进行分析。如果数据为正态分布,则以mean + SD表示;否则,它们被表示为每个变量的中位数(最小-最大)。社会科学统计软件包22.0版(IBM SPSS Corp.;Armonk, NY, USA)进行统计分析。结果:新生儿脐带血清学结果(IgM和IgG)以无反应为主,其中IgM无反应43例(97.7%),IgG无反应37例(84.1%)。在无COVID-19症状的母亲中,新生儿脐带血清学结果以非反应性IgM(88.6%)和IgG(79.5%)为主。在COVID-19康复的母亲中,新生儿脐带血清学结果也以非反应性IgM(95.5%)和IgG(81.8%)为主。结论:确诊COVID-19阳性母亲的新生儿脐带血清学结果35例(79%)多数为IgG和IgM无反应,7例(15.9%)为IgG反应,1例(2%)为IgM反应。
Serological description of neonatal umbilical cord blood from pregnant woman confirmed with positive COVID-19 by RT-PCR at Rumah Sakit Umum Pusat H. Adam Malik, Medan, Indonesia
HIGHLIGHTS
1. COVID-19 raises concern in regard with its effect on pregnancy.2. The serological descriptions of umbilical cord of neonates born from mothers suffering from COVID-19 were identified.3. Most of the serology was non-reactive IgG and IgM, followed was reactive IgG and the least was the reactive IgM.
ABSTRACT
Objective: To evaluate the serological description of the neonatal umbilical cord in COVID-19 mothers confirmed by RT-PCR at Rumah Sakit Umum Pusat (RSUP) H. Adam Malik Medan in January-June 2021.
Materials and Methods: This study was an observational study with a case series approach where the cases were mothers infected with SARS CoV-2 confirmed by RT-PCR. The study was conducted at Universitas Sumatera Utara (USU) Hospital Laboratory and RSUP H. Adam Malik for 6 months, from January 2021 to June 2021. The data collected were analyzed using descriptive statistics. If the data were normally distributed, they were presented as mean + SD; otherwise, they were presented as median (min-max) for each variable. The Statistical Package for Social Sciences version 22.0 (IBM SPSS Corp.; Armonk, NY, USA) was used for statistical analysis.
Results: Neonatal umbilical cord serology results (IgM and IgG) were predominantly non-reactive, where IgM was non-reactive in 43 neonates (97.7%) and IgG was non-reactive in 37 neonates (84.1%). In mothers without COVID-19 symptoms, neonate umbilical cord serology results were dominated by non-reactive IgM (88.6%) and IgG (79.5%). In mothers who recovered from COVID-19, neonate umbilical cord serology results were also dominated by non-reactive IgM (95.5%) and IgG (81.8%).
Conclusion: The neonatal umbilical cord serology results from the mother confirmed with positive COVID-19 were nonreactive IgG and IgM in the majority of 35 (79%) samples, reactive IgG in 7 (15.9%), and reactive IgM in 1 (2%) sample.