利用计算工具评价PcsB作为潜在候选疫苗

Sakshi Jain
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引用次数: 0

摘要

无乳链球菌/GBS是一种导致婴儿和成人许多严重感染的生物。无乳链球菌(Streptococcus Agalactiae)是一种革兰氏阳性细菌,可引起新生儿肺炎、败血症、脑膜炎以及骨骼和关节感染[1]。奶牛的亚临床乳腺炎通常是由无乳链球菌引起的。这是一种可以用多种抗生素治疗的乳腺寄生虫。在这项研究中,生物信息学工具被用来发现PcsB是否可以作为一种很好的候选疫苗来对抗这种疾病。如果根据结果所期望的蛋白质可以作为一种良好的候选疫苗,那么它可以进一步研究。
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Evaluation of PcsB as Potential Vaccine Candidate Using Computational Tools
Streptococcus agalactiae/GBS is an organism that is responsible for many severe infections in infants as well as in adults. Streptococcus Agalactiae is a gram-positive bacterium that causes pneumonia, sepsis, and meningitis in newborns, as well as infections of the bones and joints [1]. Subclinical mastitis in dairy cattle is commonly caused by Streptococcus Agalactiae. It's a mammary parasite that can be treated with a variety of antibiotics. In this study a bioinformatics tool was used to find out if PcsB can be a good vaccine candidate to combat the disease. If according to results the desired protein can be a good vaccine candidate then it can be studied further.
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来源期刊
CiteScore
0.60
自引率
10.00%
发文量
69
审稿时长
12 weeks
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