老年COVID - 19患者贫血与死亡率的关系

Mercan Taştemur, G. Arık, Hilal Heybeli̇, H. Selvi Öztorun, K. Silay, I. Ateş, Denizcan Hastürk, Busra Betul Cagir, R. Tuna Doğrul, Atacan Aras, E. Özenç
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摘要

背景:2019冠状病毒病以其不同的表现和不开明的方面继续影响着整个世界。老年患者是风险最大的群体。低血红蛋白水平导致COVID - 19感染期间缺氧,并增加并发症的风险,特别是在高危人群中。在这项研究中,我们旨在调查老年COVID - 19患者贫血的患病率及其对死亡率的影响。材料与方法:选取2020年8月- 10月在我院新冠肺炎分科内科随访的251例65岁以上患者为研究对象。贫血的定义是入院时男性血红蛋白水平为13mg /dl,女性血红蛋白水平低于12mg /dl。比较患者的人口学、实验室资料及血红蛋白水平。结果:251例新冠肺炎患者的平均年龄为75.6±7.6岁。女性115例(45.8%),136例(54.2%)。51.8%的患者患有贫血,而在因COVID - 19死亡的患者中,贫血的发生率为67.9%。多因素logistic回归分析,高龄患者(OR=1.082;95%可信区间= 1.03 - -1.137;p=0.002),存在贫血(OR=1.969;95%可信区间= 1.113 - -4.246;p=0.034),高血压(OR =5.763;95%可信区间= 1.713 - -19.389;p=0.005),痴呆(OR=3.614;95%可信区间= 1.128 - -11.578;p=0.031)作为预测COVID-19患者死亡率的独立危险因素。结论:在我们的研究中,高龄、贫血、高血压和痴呆是COVID - 19感染死亡的İndependant危险因素。老年Covid - 19患者入院时的血红蛋白水平可能有助于预测死亡率。
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The Relationship Between Anemia and Mortality in Elderly COVID 19 Patients
Background: COVID 19 continues to affect the whole world with its different presentations and unenlightened aspects.Older patients are the group most at risk. Low hemoglobin levels contribute to hypoxia during COVID 19 infection and increase the risk of complications, especially in risky groups. In this study, we aimed to investigate the prevalence of anemia and its effect on mortality in geriatric COVID 19 patients. Materials and Methods: Data of 251 patients over the age of 65 who were followed up in the Internal Medicine services allocated for COVID 19 of our hospital between August and October 2020, were included in the study. Anemia was defined as a hemoglobin level of 13 mg/dl in men and below 12 mg/dl in women at the time of admission. Demographic and laboratory data of the patients and hemoglobin levels were compared. Results: The mean age of 251 COVID-19 patients included in the study was 75.6±7.6 years. 45.8% (n:115) of the patients were female and 54.2% (n:136). While 51.8% of the patients had anemia, the presence of anemia was found to be 67.9% in patients who died due to COVID 19. According to multivariate logistic regression analysis, advanced age (OR=1.082; 95% CI=1.03-1.137; p=0.002), presence of anemia (OR=1.969; 95% CI=1.113-4.246; p=0.034),hypertension (OR =5.763; 95% CI=1.713-19.389; p=0.005), dementia (OR=3.614; 95% CI=1.128-11.578; p=0.031) were determined as independent risk factors predicting mortality in patients with COVID-19. Conclusion: Advance age, presence of anemia, hypertension and dementia has been found as İndependant risk factors for mortality in COVID 19 infection in our study. In elderly Covid 19 patients hemoglobin levels at admission may be helpful in predicting mortality.
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