尼日利亚西北部卡齐纳州一些当地水果中重金属暴露的致癌和非致癌健康风险评估

A. I. Yaradua, J. I. Bungudu, L. Shuaibu, A. Nasir, A. Usman, U. Bello, Z. Suleiman, I. Yaradua
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摘要

本研究旨在评价尼日利亚卡齐纳州一些当地水果样品中重金属(Cr、Cd、Fe、Ni、Mn、Pb和Zn)的污染负荷及其对人群健康的危害。结果表明,除Pb(1.152 ~ 1.623)和Cd(0.053 ~ 0.092)的平均浓度外,铁(1.728 ~ 1.954)、锰(0.321 ~ 0.502)和锌(0.263 ~ 0.967 ppm)的平均浓度(mg/kg)范围值普遍低于这些金属的最大允许浓度。所有被评估的重金属对人群的风险水平均低于1(< 1),表明对人群没有非致癌性的不良健康影响。所有样本水果中重金属Cd的终生癌症增量风险均在阈值风险限值(>10−4),而Pb对成人和Pb和Cd对儿童均在中等风险限值(>10−3)内。所研究水果的累积致癌风险(∑ILCR)在成人中等风险水平(>10−3)内,在儿童中等风险水平(>10−2)以上。研究结果表明,卡齐纳州当地水果的摄入是一个公共卫生问题,因为它可能导致人口癌症病例的增加。
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Evaluation of Carcinogenic and Non-Carcinogenic Health Risk of Heavy Metal Exposures from Some Local Fruits in Katsina State, North West Nigeria
This work was carried out to evaluate the heavy metals (Cr, Cd, Fe, Ni, Mn, Pb and Zn) pollution load and health risks to the population of some local fruit samples in Katsina state Nigeria. Results from this study have shown that except for the mean concentration of Pb (1.152-1.623) and Cd (0.053-0.092), the mean concentration (mg/kg) range values of Fe (1.728-1.954), Mn (0.321-0.502) and Zn (0.263-0.967 ppm) in the samples were generally below the maximum allowable concentration for these metals. The risk level of Target Hazard Quotient below 1(< 1) was recorded for all the evaluated heavy metals for the population, indicating a no non-carcinogenic adverse health effect on the population. The Incremental Lifetime Cancer Risk for the heavy metal Cd was at the threshold risk limit (>10−4) in all the sampled fruits in adults, while Pb for adults and Pb and Cd for children were within the moderate risk limit (>10−3). The cumulative cancer risk (∑ILCR) of the studied fruits was within the moderate risk level (>10−3) in adults and above the level (>10−2) in children. The results of the study have suggested that the intake of the local fruits in Katsina State is of public health concern as it may lead to an increase in the population cancer cases.
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