固体脂质纳米颗粒在癌症治疗中的应用

V. Mathur, Yamini Satrawala, M. Rajput, Piyush Kumar, P. Shrivastava, Akhilesh Vishvkarma
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引用次数: 31

摘要

固体脂质纳米颗粒在医学和更具体的药物输送中的应用将迅速普及。目前,许多药物正在研究中,更具体地说,用于癌症治疗的技术是癌症治疗的最新趋势。它帮助药剂师制定具有最大治疗价值和最小或可忽略的副作用范围的产品。癌症是一类以细胞的异常生长和不受控制的增殖为特征的疾病,抗癌药物的一个主要缺点是对肿瘤组织缺乏选择性,这导致严重的副作用和治愈率低。因此,传统的给药系统方法很难靶向异常细胞。与这些方法相协调,本综述的基本方法是固体脂质纳米颗粒的定义特征嵌入在它们对患者护理的突破性潜力中。本文综述了利用固体脂质纳米颗粒技术进行肿瘤靶向药物治疗的可能途径。我们研究了固体脂质纳米颗粒作为癌症治疗工具的实用性。关键词:肿瘤治疗;固体脂质纳米颗粒;量子点。
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Solid lipid nanoparticles in cancer therapy
The use of solid lipid nanoparticles in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy technology is the latest trend in the cancer therapy. It helps the pharmacist to formulate the product with maximum therapeutic value and minimum or negligible range side effects. Cancer is a class of disorders characterized by abnormal growth of cells that proliferate in an uncontrolled way and a major disadvantage of anticancer drugs is their lack of selectivity for tumor tissue, which causes severe side effects and results in low cure rates. Thus, it is very hard to target the abnormal cells by the conventional method of the drug delivery system. In harmony with these approaches, this review’s basic approach is that the defining features of solid lipid nanoparticles are embedded in their breakthrough potential for patient care. This review article describes the possible way to exploit solid lipid nanoparticle technology to targeted drug therapy in cancer. We looked at the usefulness of solid lipid nanoparticles as a tool for cancer therapy. Keywords: Cancer therapy; Solid lipid nanoparticles; Quantum dots.
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