共释放材料:药物发现的治疗意义和挑战

M. Faizan, Niaz Muhammad
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引用次数: 1

摘要

自上个世纪以来,一氧化碳(CO)因其无色、无味、有毒的性质而被普遍认为是威胁生命的“无声杀手”。Haldane通过血红蛋白解离参数探讨了CO作为car-box血红蛋白(COHb)的毒性[2,3]。这项研究解释了CO在哺乳动物系统中的生物学作用。
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CO-Releasing Materials: Therapeutic Implications and Challenges towards Drug Discovery
Since last century, carbon monoxide (CO) generally regarded as “silent killer” and life-threatening for living organisms because of its colourless, odourless and poisonous nature [1]. Haldane explored the poisonous nature of CO can be exerted as car-boxy hemoglobin (COHb) through hemoglobin dissociation parameters [2,3]. This study explains the biological role of the CO inside the mammalian systems.
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