Leila H. Sayed, Hossam Mohamed, Sary Khaleel Abd Elghaffar, Gamal Badr
{"title":"链脲佐菌素诱导的1型糖尿病小鼠睾丸损伤的治疗潜力","authors":"Leila H. Sayed, Hossam Mohamed, Sary Khaleel Abd Elghaffar, Gamal Badr","doi":"10.21608/aunj.2022.134540.1008","DOIUrl":null,"url":null,"abstract":"Diabetes Mellitus (DM) is a metabolic disorder that has serious effects for male fertility. Additionally, DM mediates impairment of spermatogenesis; decrease in sperm count, viability, and motility; and apoptosis in both somatic and germ cells. This study aimed to investigate the dietary effect of bee gomogenat (BG) supplementation on the architecture of testis in a mouse model of streptozotocin (STZ)-induced type 1 diabetes (TID). Mice were allocated to three different groups: control non-diabetic, YAP+ Leydig cells and the testosterone level. Furthermore, Treatment of diabetic","PeriodicalId":8568,"journal":{"name":"Assiut University Journal of Multidisciplinary Scientific Research","volume":"145 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Therapeutic potential of Bee gomogenat against testicular damage in a streptozotocin- induced type I diabetic mouse model\",\"authors\":\"Leila H. Sayed, Hossam Mohamed, Sary Khaleel Abd Elghaffar, Gamal Badr\",\"doi\":\"10.21608/aunj.2022.134540.1008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Diabetes Mellitus (DM) is a metabolic disorder that has serious effects for male fertility. Additionally, DM mediates impairment of spermatogenesis; decrease in sperm count, viability, and motility; and apoptosis in both somatic and germ cells. This study aimed to investigate the dietary effect of bee gomogenat (BG) supplementation on the architecture of testis in a mouse model of streptozotocin (STZ)-induced type 1 diabetes (TID). Mice were allocated to three different groups: control non-diabetic, YAP+ Leydig cells and the testosterone level. Furthermore, Treatment of diabetic\",\"PeriodicalId\":8568,\"journal\":{\"name\":\"Assiut University Journal of Multidisciplinary Scientific Research\",\"volume\":\"145 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Assiut University Journal of Multidisciplinary Scientific Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21608/aunj.2022.134540.1008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Assiut University Journal of Multidisciplinary Scientific Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/aunj.2022.134540.1008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Therapeutic potential of Bee gomogenat against testicular damage in a streptozotocin- induced type I diabetic mouse model
Diabetes Mellitus (DM) is a metabolic disorder that has serious effects for male fertility. Additionally, DM mediates impairment of spermatogenesis; decrease in sperm count, viability, and motility; and apoptosis in both somatic and germ cells. This study aimed to investigate the dietary effect of bee gomogenat (BG) supplementation on the architecture of testis in a mouse model of streptozotocin (STZ)-induced type 1 diabetes (TID). Mice were allocated to three different groups: control non-diabetic, YAP+ Leydig cells and the testosterone level. Furthermore, Treatment of diabetic
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