西非布基纳法索波哥大区社区医院细菌性化脓性急性中耳炎的治疗和管理

M. Sanou, Ky, A. Ba, Tamini, L. Toguyéni, Ouedraogo A-S, A. Konkobo, F. Bakiono, R. CompaoreT, M. NagaloB, C. Bissye, R. Yokoda, J. BoradM, I. Sanou, L. Sangaré, Ouédraogo, R. Traoré, J. Simporé
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摘要

背景:这是在Bogodogo地区社区医院耳鼻喉科(ORL)和国家公共卫生实验室细菌学/病毒学部门进行的一项横断面研究的描述性简短报告。本研究旨在深入了解化脓性急性中耳炎(PAOM)患者的抗生素处方质量,以建立更好的治疗和管理当地人群的健康。方法与发现:于2014年6月至2015年1月进行横断面调查。在这里,我们报告并纳入了58例在Bogodogo区社区医院耳鼻喉科诊断为化脓性急性中耳炎的未使用抗生素患者的分析。31例患者年龄在15岁以上。男性为优势群体,性别比为1.3。从患者标本中分离出62株细菌,其中葡萄球菌、肠杆菌科和假单胞菌分别占37.1%、32.2%和22.6%。在所检测的抗生素中,庆大霉素(98%)、环丙沙星(97%)、亚胺培南(82%)和第三代头孢曲松(76%)4类有效。但对氨苄西林和阿莫西林+克拉维酸的敏感性很低。结论:自我用药、过度使用不必要的药物是导致抗生素耐药的原因之一。我们能够确定化脓性急性中耳炎的主要细菌,并希望这项产生数据的努力将有助于改善对布基纳法索和撒哈拉以南非洲以外地区患者的护理。
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Treatment and Management of BacterialPurulent Acute Otitis at the BogodogoDistrict Community Hospital,Burkina Faso, West Africa
Background: This is a descriptive short report of a cross-sectional study conducted in the Otorhinolaryngology unit (ORL) of the Bogodogo district community hospital and in the Unit of Bacteriology/Virology of the National Laboratory of Public Health. This study sought to provide insight into the quality of antibiotic prescribing in patients with purulent acute otitis media (PAOM) to establish a better treatment and management of local population ‘health. Methods and findings: A cross-sectional investigation was carried out from June 2014 to January 2015. Here, we reported and included in the analysis 58 cases of antibiotic-naive patients diagnosed with purulent acute otitis media seen in the otorhinolaryngology unit of the Bogodogo district community hospital. Thirtyone (31) patients were over 15 years. Males were the dominant group with a sex ratio of 1.3. Sixty-two (62) bacterial strains were isolated from patient samples of which Staphylococci, Enterobacteriaceae and Pseudomonas accounted for 37.1%, 32.2% and (22.6%), respectively. Among the antibiotics tested, four (4) classes proved effective: Gentamycin (98%), Ciprofloxacin (97%), Imipenem (82%) and the 3rd generation of Ceftriaxone (76%).However, the sensitivity to Ampicillin and Amoxicillin + clavulanic acid was very low. Conclusions: Self-medicating, over-prescribing unnecessary drugs are among the cause of resistance to antibiotic treatment. We were able to identify the main bacteria involved in purulent acute otitis and hope this effort of generating data will be useful to improve the care for patient in Burkina and beyond in Sun- Saharan Africa.
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