golimomab治疗成人关节慢性炎症疾病:临床效能和耐受性

Н. В. Чичасова
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引用次数: 0

摘要

由于最近将golimumab引入儿科风湿病实践,对这种肿瘤坏死因子α抑制剂的临床研究进行了概述,其中大多数是针对患有风湿病的成人患者进行的。临床实验室效果和皮下注射形式的golimumab的耐受性已分析类风湿关节炎,银屑病关节炎和脊柱炎。在长期观察性研究(长达5年)中评估golimumab的疗效和耐受性已经进行了讨论。
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Голимумаб в лечении хронических воспалительных заболеваний суставов во взрослой популяции: клиническая эффективность и переносимость
Due to the recent introduction of golimumab into paediatric rheumatology practice, an overview of the clinical studies of this tumour necrosis factor alpha inhibitor, most of which were conducted with adult patients with rheumatic diseases, has been presented. Clinical laboratory effects and tolerability of golimumab in the form of subcutaneous injections have been analysed for rheumatoid arthritis, psoriatic arthritis, and spondylitis. Evaluation of the efficacy and tolerability of golimumab in long-term observational studies (up to 5 years) has been discussed.
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