To the question of S.S. Zimnitsky on the origin of the giant T wave after ventricular extrasystole on an electrocardiogram

The study of life, medical and scientific activities of the outstanding domestic scientist S.S. Zimnitsky always causes and will cause great interest. The versatility of his talent as a scientist continues to amaze. Many of the issues that remain relevant today raised by S.S. Zimnitsky, not fully resolved in the XXI century. There were no answers to the well-known question asked by the seriously ill S.S. Zimnitsky to another prominent Russian scientist, the beacon of Russian physiological science — A.F. Samoilov. This question concerned the origin of the giant positive T wave in the first QRS complex after the ventricular extrasystole on the electrocardiogram. The question remained unanswered. We believe that this was because by the end of the 20s of the XX century (S.S. Zimnitsky died in 1927), the delicate mechanisms of repolarization processes were not able to understand, in both healthy and diseased myocardium. The article sets forth our original point of view on the genesis of such a T wave in S.S. Zimnitsky. We believe that a scientific discussion on this issue is quite possible. There is no doubt that both life and scientific activities of S.S. Zimnitsky has always attracted and will attract the attention of both medical historians and practical doctors, scientists and inquisitive students.