{"title":"前列腺平滑肌肉瘤1例并文献复习","authors":"A. Dubey, G. Sivananthan, T. Bradel, R. Koul","doi":"10.5580/195d","DOIUrl":null,"url":null,"abstract":"Majority of the prostate malignancies are adenocarcinoma in nature. Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% -3.7% of primary prostate malignancies. Prostate sarcomas are diagnostically and therapeutically very challenging. This neoplasm is a mesenchymal tumor that originates from smooth muscles of prostate and periprostatic tissue. We present a patient with primary leiomyosarcoma of the prostate and review of literature. The factors predictive of long-term survival are negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this rare entity. The most effective treatment, if feasible, is radical surgery. The role of adjuvant treatments and their effects in terms of increasing local control, over all survival or disease free survival is not clearly defined in literature.","PeriodicalId":22534,"journal":{"name":"The Internet Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2010-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"Prostatic Leiomyosarcoma –A Rare Case Report With Review Of Literature\",\"authors\":\"A. Dubey, G. Sivananthan, T. Bradel, R. Koul\",\"doi\":\"10.5580/195d\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Majority of the prostate malignancies are adenocarcinoma in nature. Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% -3.7% of primary prostate malignancies. Prostate sarcomas are diagnostically and therapeutically very challenging. This neoplasm is a mesenchymal tumor that originates from smooth muscles of prostate and periprostatic tissue. We present a patient with primary leiomyosarcoma of the prostate and review of literature. The factors predictive of long-term survival are negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this rare entity. The most effective treatment, if feasible, is radical surgery. The role of adjuvant treatments and their effects in terms of increasing local control, over all survival or disease free survival is not clearly defined in literature.\",\"PeriodicalId\":22534,\"journal\":{\"name\":\"The Internet Journal of Oncology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Internet Journal of Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5580/195d\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet Journal of Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/195d","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Prostatic Leiomyosarcoma –A Rare Case Report With Review Of Literature
Majority of the prostate malignancies are adenocarcinoma in nature. Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% -3.7% of primary prostate malignancies. Prostate sarcomas are diagnostically and therapeutically very challenging. This neoplasm is a mesenchymal tumor that originates from smooth muscles of prostate and periprostatic tissue. We present a patient with primary leiomyosarcoma of the prostate and review of literature. The factors predictive of long-term survival are negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this rare entity. The most effective treatment, if feasible, is radical surgery. The role of adjuvant treatments and their effects in terms of increasing local control, over all survival or disease free survival is not clearly defined in literature.