前列腺平滑肌肉瘤1例并文献复习

A. Dubey, G. Sivananthan, T. Bradel, R. Koul
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引用次数: 6

摘要

大多数前列腺恶性肿瘤本质上是腺癌。前列腺平滑肌肉瘤是一种极为罕见且侵袭性很强的肿瘤,占原发性前列腺恶性肿瘤的比例不到0.1% -3.7%。前列腺肉瘤的诊断和治疗都非常具有挑战性。这种肿瘤是一种起源于前列腺平滑肌和前列腺周围组织的间质肿瘤。我们报告一位原发性前列腺平滑肌肉瘤患者并复习文献。预测长期生存的因素是阴性手术切缘和无转移性疾病。多学科的方法是必要的适当管理这种罕见的实体。如果可行,最有效的治疗方法是根治性手术。辅助治疗的作用及其在增加局部控制、总体生存或无病生存方面的作用在文献中没有明确定义。
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Prostatic Leiomyosarcoma –A Rare Case Report With Review Of Literature
Majority of the prostate malignancies are adenocarcinoma in nature. Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% -3.7% of primary prostate malignancies. Prostate sarcomas are diagnostically and therapeutically very challenging. This neoplasm is a mesenchymal tumor that originates from smooth muscles of prostate and periprostatic tissue. We present a patient with primary leiomyosarcoma of the prostate and review of literature. The factors predictive of long-term survival are negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this rare entity. The most effective treatment, if feasible, is radical surgery. The role of adjuvant treatments and their effects in terms of increasing local control, over all survival or disease free survival is not clearly defined in literature.
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