拉什特2型糖尿病患者尿酸水平和血糖状态的评价

M. Yaseri, Seyyede Sahere Mortazavi, N. Faraji
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摘要

背景:糖尿病是最常见和最昂贵的慢性疾病之一,在世界各地的患病率不断上升。另一方面,2型糖尿病患者尿酸(UA)水平与血糖指数之间的关系尚不清楚。目的:探讨2型糖尿病患者尿酸水平与血糖状态的关系。方法:在这项横断面研究中,共研究了230例2型糖尿病患者,这些患者于2020年转诊到Razi和Besat诊所。使用研究者制作的检查表收集人口统计学和临床数据,包括年龄、性别、疾病持续时间、体重指数(BMI)、空腹血糖(FBS)、胆固醇、甘油三酯(TG)、高密度脂质(HDL)、低密度脂质(LDL)、血红蛋白A1C (HbA1c)、UA、肌酐(Cr)水平、心脏病史、血压和吸烟史。使用IBM SPSS Statistics version 26对结果进行分析。结果:UA与HbA1C (r = 0.318, P<0.001)、Cr (r = 0.351, P<0.001)、甘油三酯(TG) (r = 0.174, P=0.008)存在显著相关性。结论:一般情况下,2型糖尿病患者血清UA水平对血糖状态有不利影响。
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Evaluation of Uric Acid Level and Glycemic Status in Type 2 Diabetic Patients in Rasht
Background: Diabetes is one of the most common and costly chronic diseases with an increasing prevalence in all around the world. On the other hand, the relationship between Uric Acid (UA) level and glycemic index in type 2 diabetic patients is not clear. Objective: The aim of this study is to evaluate the UA level and glycemic status of type 2 diabetic patients. Methods: A total of 230 patients with type 2 diabetes were studied in this cross-sectional study, who referred to Razi and Besat clinics in 2020. Researcher-made checklist were used to collect demographic and clinical data includes age, sex, duration of the disease, body mass index (BMI), fasting blood sugar (FBS), Cholesterol, Triglyceride (TG), high density lipid (HDL), low density lipid (LDL), Hemoglobin A1C (HbA1c), UA, Creatinine (Cr) level, history of heart disease, blood pressure, and a history of smoking. The results were analyzed using IBM SPSS Statistics version 26. Results: The results showed that there was a marginally significant relationship between UA and HbA1C (r = 0.318, P<0.001), Cr (r = 0.351, P<0.001) and Triglyceride (TG) (r = 0.174, P=0.008). Conclusion: Generally, in patients with type 2 diabetes, serum UA level has an adverse effect on glycemic status.
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