气管、支气管腺样囊性癌50例临床分析

Yanfeng Fang, Yansheng Liu, Y. Nan, Wei Liu, Hongjun Zhang, Yani Sun, F. Jin
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摘要

目的探讨气管、支气管腺样囊性癌的部分临床特点及支气管镜腔内介入治疗的临床价值。方法总结2010年1月至2018年7月第四军医大学唐都医院诊断、治疗并随访的气管、支气管腺样囊性癌患者50例。将其分为支气管镜介入组(24例)和手术组(26例),回顾性分析其部分临床特点及支气管镜腔介入治疗与手术治疗效果的比较。结果女性30例,男性20例,中位年龄49.62岁。50例患者均以咳嗽、咳痰、气短为主要症状,部分患者伴咯血、胸痛。50例中,23例发生在支气管中下段,占全部病例的最大比例。Borg指数Ⅰ级8例,Ⅱ级18例,Ⅲ级11例,Ⅳ级13例。26例为首次手术,24例为首次接受两种以上支气管镜腔内介入治疗。两组气管、支气管狭窄缓解率比较,差异无统计学意义(χ2=6.019, P=0.111)。支气管镜腔介入治疗后的Borg指数(Z=-4.622, P<0.001)和手术后的Borg指数(Z=-5.553, P<0.001)均有改善,差异有统计学意义。1例接受支气管镜腔介入治疗,在治疗过程中出现严重出血。结论有呼吸短促症状的未手术患者经支气管镜干预可降低呼吸短促指数,缓解呼吸短促,且患者狭窄程度较高。值得临床推广。关键词:胸外科手术;气管腺样囊性癌;电子支气管镜
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Clinical experience of 50 cases of adenoid cystic carcinoma of trachea and bronchi
Objective To study the part of clinical characteristics of trachea or bronchi adenoid cystic carcinoma and clinical value of the bronchoscopy cavity interventional therapy about it. Methods This study summarized total 50 patients of tracheal or bronchus adenoid cystic carcinoma who are diagnosed, treated and carefully followed in Tangdu hospital, The Fourth Military Medical University from January 2010 to July 2018.They were divided into bronchoscope intervention group (24 cases) and operation group (26 cases) And a retrospective analysis was then performed with their part of clinical characteristics and the comparison of therapeutic effect between the bronchoscopy cavity interventional therapy and the surgery. Results There were 30 females and 20 males and the median age was 49.62 years old.The main symptoms of all 50 cases were cough, expectoration and shortness of breath and some of them also accompany with hemoptysis and chest pain.Among 50 cases, 23 cases of carcinoma occurred in middle-to-lower bronchial segments, which is the largest part of all cases.8 cases scored grade Ⅰ at Borg index, 18 cases scored grade Ⅱ, 11 cases scored grade Ⅲ, and 13 cases scored grade Ⅳ.26 patients accepted surgery for the first time, and the other 24 patients accepted more than two kinds of bronchoscopy cavity interventional therapy for the first time.And the trachea or bronchi stenosis remission rate between two groups had no statistically difference (χ2=6.019, P=0.111). The Borg index after the bronchoscopy cavity interventional therapy (Z=-4.622, P<0.001) and the surgery (Z=-5.553, P<0.001) were both improved, and the difference was statistically significant.There was one case accepted the bronchoscopy cavity interventional therapy had a bad hemorrhage during the therapy. Conclusions Shortness of breath, unoperated patients with symptoms of bronchoscopy intervention can reduce the shortness of breath index, relieve shortness of breath, and the degree of stenosis of the humen is high.It is worthy of chlinical promotion. Key words: Thoracic surgical procedures; Adenoid cystic carcinoma of trachea; Electronic bronchoscope
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