鞍上区共存肿瘤一例及文献复习

Halil Can KÜÇÜkyildiz, Giray Güneş, F. Koç, Ü. Özüm
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摘要

摘要颅内原发肿瘤同时存在于不同细胞类型实属罕见。虽然文献中经常报道脑膜瘤和胶质瘤的关联,但脑膜瘤和表皮样囊肿的病例数量相对较少。我们报告一个独特的病例,因为鞍上脑膜瘤和表皮样囊肿的关联在以前的文献中没有报道过。病例介绍:一名50岁女性,因头痛和进行性视力丧失而就诊。在颅磁共振(MR)图像中,观察到T1A低信号,T2A等高信号异质对比鞍上肿块病变。手术诊断为鞍上脑膜瘤。术中偶然发现鞍上区一肿块,其宏观表现与表皮样囊肿相符。两种不同的病理标本送病理室。患者的病理报告为WHO 2021,过渡型1级脑膜瘤和表皮样囊肿内容物。结论:文献中脑膜瘤和表皮样囊肿的病例数很少。尽管有先进的磁共振成像技术,但囊性病变在诊断中可能被忽视。在同一部位出现两种不同的组织病理类型的肿瘤,可以用肿瘤的局部旁分泌效应来解释。
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Co-existing Tumors On Suprasellar Region : A Rare Case and Review of Literature
Introduction: The co-existence of primary intracranial tumors originating from different cell types is rare. While the association of meningioma and glioma is frequently reported in the literature, the number of cases with meningiomas and epidermoid cysts is relatively low. We report a unique case because the association of supra-sellar meningioma and the epidermoid cyst has not been reported before in the literature. Case Presentation: A 50-year-old female presented to the clinic with a headache and progressive vision loss. In cranial Magnetic Resonance (MR) images, a T1A hypointense, T2A iso-hyper intense heterogenous contrasting suprasellar mass lesion was observed. The patient was operated on with a diagnosis of suprasellar meningioma. At the suprasellar region, a mass that macroscopic view and consistency compatible with epidermoid cyst ex-plored intraoperative incidentally. Two different pathological specimens were sent to pathology. The patient's pathology was reported as WHO 2021, Transitional type grade 1 Meningioma, and Epidermoid cyst content. Conclusion: The number of cases with meningiomas and epidermoid cysts is very low in the literature. Despite advanced MR imaging techniques, cystic lesions can be overlooked in the diagnosis. The occurrence of two different histopathological types of tumors in the same localization can be explained by the local paracrine effects of the tumors.
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