[改性同位素水对体内自由基氧化参数的影响]。

A. Basov, M. Baryshev, S. Dzhimak, I. Bykov, R. Sepiashvili, I. I. Pavliuchenko
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引用次数: 2

摘要

利用核磁共振技术研究了同位素含量改变的水对血液中氘组成的影响,评估了长时间氧化应激下血液和冻干组织(肝、肾)中促氧化-抗氧化系统的状态。讨论了同位素含量改变水的直接和间接抗氧化作用的可能机制,以及在特殊生理条件和临床实践中对氧化代谢异常的营养纠正的前景。
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[The effect of water with modified isotope content on the parameters of free radical oxidation in vivo].
With the use of nuclear magnetic resonance we investigated the effect of consumption of water with the modified isotope content on the composition of deuterium in the blood, assessed the state of pro-oxidant-antioxidant system in the blood and lyophilized tissues (liver, kidneys) under prolonged oxidative stress. Possible mechanisms of direct and indirect antioxidant effects of the water with modified isotope content and the perspectives of its use for nutritional correction of abnormalities of oxidative metabolism during special physiological conditions and in clinical practice are discussed.
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