睾丸原发性弥漫性大b细胞淋巴瘤1例

Stevan Kristian Lionardi, Nicholas Andrian Singgih, Lutfi Bagus
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摘要

目的:报告1例睾丸非霍奇金淋巴瘤的治疗经验。病例描述:一名55岁男性来到泌尿科门诊,主诉左侧无痛睾丸肿大,肿块重。泌尿科检查发现左侧单侧睾丸肿大,睾丸大小10x7x7cm,边界牢固,致密,无压痛。患者随即接受左睾丸切除术。组织学和免疫组化检查发现非霍奇金B细胞(CD20+)高分级,非gcb。讨论:在本病例中,患者接受了睾丸切除术和CHOP化疗方案的治疗。然而,在左侧腹股沟区发现一个柔软的肿块,由于怀疑转移,这是一个不寻常的表现,并通过组织学和免疫组织化学检查进一步证实。结论:原发性睾丸淋巴瘤伴弥漫大b细胞淋巴瘤(DLBCL)亚型是一种罕见的疾病。睾丸非霍奇金淋巴瘤的初始治疗选择是睾丸切除术,然后联合化疗以改善预后。关键词:睾丸切除术,睾丸淋巴瘤,睾丸肿瘤。
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PRIMARY DIFFUSE LARGE B CELL LYMPHOMA OF TESTICULAR : A CASE REPORT
Objective: To report our experience in treating a case of Testicular non-Hodgkin Lymphoma. Case(s) Presentation: A 55-year-old man came to the urology outpatient clinic with complaints of an enlarged left painless testicle that was lumpy and heavy.  Urological examination found left unilateral testicle enlargement testicle, the size measured 10x7x7 cm with firm borders, solid consistency, and no tenderness. The patient then was treated with left orchiectomy. Histology and Immunohistochemical examination found non-Hodgkin B cells (CD20+) high grade, non-GCB. Discussion: In this case, the patient was treated with orchiectomy followed by a CHOP chemotherapy regimen. However, there was an unusual presentation due to the suspicion of metastases through the findings of a tender lump in the left inguinal region which was further confirmed by histological and immunohistochemical examination. Conclusion: Primary testicular lymphoma with a subtype of DLBCL (Diffuse Large B-Cell Lymphoma) is a rare disease. Orchiectomy is the initial treatment option for Testicular non-Hodgkin Lymphoma followed by combination therapy of chemotherapy to improve the prognosis. Keywords: Orchiectomy, testicular lymphoma, testicular tumors.
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