急性髓系白血病患者线状IgA大疱性皮肤病:罕见病例报告。

Deisy Vania Kianindra, A. Rosa, Dina Pebriany, W. Dewiyanti, A. Madjid
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引用次数: 0

摘要

线性IgA大疱性皮肤病(LABD)是一种罕见的自身免疫性大疱性疾病,其特征是IgA沿皮肤基膜呈线性沉积。在儿童中,LABD典型表现为“宝石簇”外观,而在成人中,典型表现为瘙痒丘疹,红斑基础上有紧张的囊泡和大泡。我们报告一例41岁女性LABD,我们怀疑是由急性髓性白血病引起的,表现为多个囊泡和大泡合并,形成LABD的典型临床表现,并经组织病理学和直接免疫荧光证实。患者接受口服和外用皮质类固醇联合治疗,效果良好。
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Linear IgA bullous dermatosis in an acute myeloid leukemia patient: a rare case report.
Linear IgA bullous dermatosis (LABD) is a rare autoimmune bullous disease characterized by linear IgA deposition along the skin basal membrane. In children, LABD classically presents with a "cluster of jewels" appearance, whereas in adults the classic presentation is itchy papules with tense vesicles and bullae on an erythematous base. We report the case of a 41-year-old woman with LABD that we suspect was induced by acute myeloid leukemia presenting with multiple vesicles and bullae that coalesced, forming the typical clinical manifestation of LABD and confirmed with histopathological and direct immunofluorescence. The patient was treated with a combination of oral and topical corticosteroids with excellent results.
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CiteScore
1.70
自引率
8.30%
发文量
38
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