Soetomo博士综合学术医院吸烟习惯与肺结核的关系

Balivia Andi Permata Hapsari, Prastuti Asta Wulaningrum, Rimbun Rimbun
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引用次数: 1

摘要

吸烟已被报道为结核病(TB)的危险因素之一。吸烟与结核病之间的关系已被多项研究证实,但对吸烟程度与痰涂片阳性之间的关系知之甚少。方法:采用横断面设计进行分析性观察研究。2018年1月至10月在泗水Soetomo综合医院DOTS(短期直接观察治疗)/MDR(耐多药)门诊和住院病房进行的肺结核患者数据。采用Brinkman指数(BI)测定吸烟程度。比值比(OR)和95%置信区间(CI)也进行了估计。结果:94例肺结核患者中,非吸烟者56例,吸烟者38例。轻度吸烟(P= 0,120, OR= 0.200, 95% CI: 0.022-1.823),中度吸烟(P=0.377, OR= 1.667, 95% CI: 0.533-5.209),重度吸烟(P=0.076, OR= 0.333, 95% CI: 0.96-1.160)。中度吸烟与重度吸烟作为对照(P=0.33, OR = 5.000, 95% CI=1.096-22.820)。结论:吸烟习惯与痰涂片阳性无显著相关性,但本研究证实吸烟习惯患者痰涂片阳性的机会大于不吸烟者。中度吸烟患者痰涂片阳性的机会高于重度吸烟患者。
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Association between Smoking Habit and Pulmonary Tuberculosis at Dr. Soetomo General Academic Hospita
Introduction: Smoking has been reported as one of tuberculosis (TB) risk factor. The association between smoking and TB has been proven in multiple studies, but little known about the association between smoking degree and sputum smear positive. Methods: An analytic observational study using cross-sectional design. Data of patients with pulmonary TB conducted at DOTS (Directly Observed Treatment Short course)/MDR (Multi Drug Resistance) outpatient and inpatient ward in Dr Soetomo General Hospital Surabaya from January to October 2018. The degree of smoking was measured using Brinkman Index (BI). The odds ratio (OR) and 95% confidence intervals (CI) were also estimated.Results: There were 94 patients with pulmonary TB, 56 non-smoker and 38 smoker. Light smoking (P = 0,120, OR = 0.200, 95% CI: 0.022-1.823), moderate smoking (P=0.377, OR = 1.667, 95% CI: 0.533-5.209), heavy smoking (P=0.076, OR= 0.333, 95% CI: 0.96-1.160). Moderate smoking compared to heavy smoking as a control (P=0.33, OR = 5.000, 95% CI=1.096-22.820). Conclusion: There’s no significant correlation between smoking habits and sputum smear positive, but the present study evidenced the patients with smoking habits had greater chance to get sputum smear positive than non-smokers. Patient with moderate smoking compared to heavy smoking had greater chance to get sputum smear positive.
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