巴基斯坦制造的丙型肝炎药物

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Annals of King Edward Medical University Lahore Pakistan Pub Date : 2022-08-04 DOI:10.21649/akemu.v28i2.5118
Nida Waheed, Tooba Fida, Saman Fatima, Osman Khalid Waheed
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引用次数: 0

摘要

丙型肝炎是由丙型肝炎病毒引起的世界上最普遍的肝脏疾病之一,它进一步使患者易患肝癌。这种病毒通过使用受感染的注射器、受感染的输血和与受感染个体的性接触传播。本病最初无症状,但可呈急性或慢性进行性病程。巴基斯坦的肝炎患者比例很高,每20个人中就有一人血清呈阳性。肝炎的治疗及其成功取决于通过鉴定抗HCV抗体对疾病进行早期诊断,并通过核酸扩增试验检测HCV RNA进一步确认疾病。Ferozsons制药公司因在巴基斯坦引进有效的丙型肝炎治疗而受到赞誉,这些治疗最初是昂贵的。然而,随着新的和更好的药物的发展,成本有效地降低了,现在低收入的人也能负担得起这种治疗。政府采取了许多行动,对个人进行了大规模筛查,并提供了适当和及时的药物。根除丙型肝炎的另一个重要步骤是通过广告、研讨会和专家举办的丙型肝炎病毒课程对公众进行教育。值得一提的是ECHO项目,因为它表明采用ECHO方法治疗的患者预后比其他方法更好。
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Hepatitis C Drugs Made in Pakistan
Hepatitis C is among the most prevalent liver diseases in the world caused by hepatitis C virus and it further predisposes the patient to liver cancers. This virus is transmitted through the use of infected syringes, infected blood transfusions and sexual contact with affected individuals. This disease is asymptomatic initially but may follow an acute or chronic progressive course. Pakistan has a significant ratio of hepatitis affected patients with every one out of 20 individuals being seropositive. The treatment of hepatitis and its success is dependent upon the early diagnosis of the disease through the identification of anti HCV antibodies and further disease confirmation by detection of HCV RNA through nucleic acid amplification tests. Ferozsons pharmaceutical company is credited with the introduction of effective Hepatitis C treatments in Pakistan which were initially were expensive. However, with the development of new and better medicines the cost reduced effectively and the treatment is now affordable by people with low income. Many actions have been taken at the government level which have made mass screening of the individuals along with appropriate and timely supply of medications possible. Another important step in eradicating Hepatitis C is the education of the public by advertisements, seminars and HCV courses conducted by specialists. Project ECHO deserves mention, as it shows that people treated according to ECHO methodology have better prognosis than the others.
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75
审稿时长
12 weeks
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