Qena大学医院变应性鼻炎患者缺铁性贫血的发生率分析

U. Taya, A. Abdelraheem, Reham Farouk Sayed, A. Selim, Mahmoud Khalefa
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摘要

背景:变应性鼻炎是一种常见的免疫源性疾病。它对患者的生活质量产生负面影响。目的:探讨变应性鼻炎患者铁谱的变化。患者和方法:本研究对30例变应性鼻炎患者进行研究。所有参与者均接受临床评估和以下调查:全血图像,血清铁蛋白,血清铁和总铁结合能力(TIBC)和IgE。采用视觉模拟评分法(VAS)评价变应性鼻炎的严重程度。结果:研究患者中男性18例(60%),女性12例(40%),平均年龄11.3±4.2 (SD)岁,平均发病年龄4.6±3.01(SD)岁,平均病程6.7±2.9年。本组患者中有8例(26.7%)有阳性家族史。重度变应性鼻炎患儿缺铁及缺铁性贫血的发生率明显高于轻度变应性鼻炎患儿。轻、中、重度变应性鼻炎患者Hb、MCH、HCT、铁蛋白、血清铁、TIBC差异均有统计学意义(p值= 0.037)。轻、中、重度患者IgE差异有统计学意义(p值= 0.015)。血清IgE与儿童变应性鼻炎的严重程度相关。结论:儿童变应性鼻炎患者缺铁性贫血的患病率高于非特应性鼻炎患者。缺铁性贫血随着变应性鼻炎的严重程度而显著增加。血清IgE与儿童变应性鼻炎的严重程度相关。
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The incidence of Iron Deficiency Anemia in Allergic Rhinitis patients in Qena University Hospital
Background: Allergic rhinitis is a common disease of immune origin. It affects the quality of life of patients negatively. Objectives: To evaluate the changes in iron profile in allergic rhinitis patients. Patients and methods : This study was conducted on thirty patients with allergic rhinitis. All of the participants were subjected to clinical evaluation and the following investigations: Complete blood picture, Serum ferritin, Serum iron and total iron binding capacity (TIBC) and IgE. Visual analogue scale (VAS) score was used to measure the severity of allergic rhinitis. Results : Among the studied patients, there were 18 males (60%) and 12 females (40%), the mean age of studied patients was 11.3 ± 4.2 (SD) years with mean onset age of 4.6 ± 3.01(SD) years and mean duration of disease of 6.7 ± 2.9 years. There were 8 patients (26.7%) with positive family history in the studied patients. The incidence of iron deficiency and iron deficiency anemia was significantly higher in children with severe allergic rhinitis compared with mild cases. Also we found statistically significant difference (p-value = 0.037) between mild, moderate & severe cases of allergic rhinitis as regard Hb, MCH, HCT, ferritin, serum iron and TIBC. A statistically significant difference (p-value = 0.015) was noted between mild, moderate & severe cases as regard IgE. Serum IgE is correlated with the severity of allergic rhinitis in children. Conclusion : Prevalence of iron deficiency anemia in pediatric patients with allergic rhinitis is higher than in patients without atopic disease. Iron deficiency anemia increases markedly with severity of allergic rhinitis. Serum IgE is correlated with the severity of allergic rhinitis in children.
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