{"title":"胆碱、泮库溴铵和维库溴铵对麻醉马神经肌肉的阻断作用及其与新斯的明的拮抗作用","authors":"L. Klein , E. Beck , J. Hopkins , B. Burton","doi":"10.1111/j.1467-2995.1982.tb00609.x","DOIUrl":null,"url":null,"abstract":"<div><p>A cumulative dose response method was used to study neuromuscular potency and duration of gallamine, pancuronium and vecuronium (ORG NC-45) in anaesthetized horses. Characteristics of the blockade and reversibility with neostigmine were compared in the 3 drugs based on responses to 2 HZ and tetanic stimulation. Recorded digital extensor responses were compared with observed responses during tetanic stimulation of the facial nerve.</p></div>","PeriodicalId":101044,"journal":{"name":"Proceedings of the Association of Veterinary Anaesthetists","volume":"10 ","pages":"Pages 173-188"},"PeriodicalIF":0.0000,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1467-2995.1982.tb00609.x","citationCount":"5","resultStr":"{\"title\":\"CHARACTERISTICS OF NEUROMUSCULAR BLOCKADE PRODUCED BY GALLAMINE, PANCURONIUM AND VECURONIUM (ORG NC-45), AND ANTAGONISM WITH NEOSTIGMINE IN ANAESTHETIZED HORSES\",\"authors\":\"L. Klein , E. Beck , J. Hopkins , B. Burton\",\"doi\":\"10.1111/j.1467-2995.1982.tb00609.x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A cumulative dose response method was used to study neuromuscular potency and duration of gallamine, pancuronium and vecuronium (ORG NC-45) in anaesthetized horses. Characteristics of the blockade and reversibility with neostigmine were compared in the 3 drugs based on responses to 2 HZ and tetanic stimulation. Recorded digital extensor responses were compared with observed responses during tetanic stimulation of the facial nerve.</p></div>\",\"PeriodicalId\":101044,\"journal\":{\"name\":\"Proceedings of the Association of Veterinary Anaesthetists\",\"volume\":\"10 \",\"pages\":\"Pages 173-188\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1982-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/j.1467-2995.1982.tb00609.x\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Association of Veterinary Anaesthetists\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0269524316300673\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Association of Veterinary Anaesthetists","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0269524316300673","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
CHARACTERISTICS OF NEUROMUSCULAR BLOCKADE PRODUCED BY GALLAMINE, PANCURONIUM AND VECURONIUM (ORG NC-45), AND ANTAGONISM WITH NEOSTIGMINE IN ANAESTHETIZED HORSES
A cumulative dose response method was used to study neuromuscular potency and duration of gallamine, pancuronium and vecuronium (ORG NC-45) in anaesthetized horses. Characteristics of the blockade and reversibility with neostigmine were compared in the 3 drugs based on responses to 2 HZ and tetanic stimulation. Recorded digital extensor responses were compared with observed responses during tetanic stimulation of the facial nerve.
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